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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GGPS1
All Species:
27.88
Human Site:
Y272
Identified Species:
51.11
UniProt:
O95749
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95749
NP_001032354.1
300
34871
Y272
K
E
L
E
A
K
A
Y
K
Q
I
D
A
R
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536340
300
34834
Y272
K
E
L
E
S
K
A
Y
K
Q
I
D
A
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTN0
300
34688
Y272
R
E
L
E
A
K
A
Y
K
Q
I
E
A
C
G
Rat
Rattus norvegicus
Q6F596
300
34759
Y272
R
E
L
E
A
K
A
Y
K
Q
I
E
A
C
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512343
301
34844
Y272
K
A
L
E
S
E
A
Y
T
Q
I
E
A
L
G
Chicken
Gallus gallus
XP_424685
420
47652
Y392
K
E
L
E
S
E
A
Y
K
Q
I
E
S
L
G
Frog
Xenopus laevis
NP_001091413
296
34032
Y272
R
E
L
E
A
E
A
Y
K
Q
I
E
S
L
G
Zebra Danio
Brachydanio rerio
NP_956329
327
37394
Y273
L
D
L
E
V
E
A
Y
R
L
I
K
E
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523958
338
38808
R284
E
S
L
D
A
E
A
R
S
E
V
A
R
L
G
Honey Bee
Apis mellifera
XP_001122899
310
35895
R281
E
E
L
D
K
K
A
R
D
E
I
A
R
L
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781061
427
48903
E302
F
D
L
E
K
Q
I
E
A
K
P
F
T
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12051
335
38633
N283
Q
I
L
E
F
D
T
N
S
L
A
Y
T
K
N
Red Bread Mold
Neurospora crassa
P24322
433
48467
R394
K
V
L
V
D
R
A
R
Q
M
T
E
D
I
D
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
98
N.A.
93.6
95
N.A.
92
64
83.6
77
N.A.
52.6
57.4
N.A.
48.2
Protein Similarity:
100
N.A.
N.A.
99.6
N.A.
97.3
97.3
N.A.
96.3
69
93.3
85
N.A.
69.8
74.1
N.A.
59.4
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
80
80
N.A.
60
66.6
66.6
40
N.A.
26.6
40
N.A.
13.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
93.3
N.A.
80
93.3
93.3
60
N.A.
60
60
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
39.7
36.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.1
50.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
39
0
85
0
8
0
8
16
39
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% C
% Asp:
0
16
0
16
8
8
0
0
8
0
0
16
8
0
8
% D
% Glu:
16
54
0
77
0
39
0
8
0
16
0
47
8
0
0
% E
% Phe:
8
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
77
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
8
0
0
0
70
0
0
8
0
% I
% Lys:
39
0
0
0
16
39
0
0
47
8
0
8
0
8
8
% K
% Leu:
8
0
100
0
0
0
0
0
0
16
0
0
0
54
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
8
0
0
0
0
8
0
0
8
54
0
0
0
0
0
% Q
% Arg:
24
0
0
0
0
8
0
24
8
0
0
0
16
16
0
% R
% Ser:
0
8
0
0
24
0
0
0
16
0
0
0
16
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
8
0
8
0
16
0
0
% T
% Val:
0
8
0
8
8
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _