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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACSL3
All Species:
31.52
Human Site:
Y391
Identified Species:
57.78
UniProt:
O95573
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95573
NP_004448.2
720
80420
Y391
P
E
I
M
D
R
I
Y
K
N
V
M
N
K
V
Chimpanzee
Pan troglodytes
XP_001166229
692
77085
Y391
P
E
I
M
D
R
I
Y
K
N
V
M
N
K
V
Rhesus Macaque
Macaca mulatta
XP_001108259
720
80350
Y391
P
E
I
M
D
R
I
Y
K
N
V
M
N
K
V
Dog
Lupus familis
XP_851617
720
80340
Y391
P
E
I
M
D
R
I
Y
K
N
V
M
N
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZW4
720
80488
Y391
P
E
I
M
D
R
I
Y
K
N
V
M
N
K
V
Rat
Rattus norvegicus
Q63151
720
80440
Y391
P
E
I
M
D
R
I
Y
K
N
V
M
N
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512270
609
67400
K311
Y
K
M
E
Q
I
S
K
G
Y
S
T
P
L
C
Chicken
Gallus gallus
XP_422625
713
79313
Y382
P
E
I
M
D
R
I
Y
K
N
V
M
N
K
V
Frog
Xenopus laevis
Q7ZYC4
739
81601
M391
W
E
K
M
Q
E
K
M
K
A
V
G
A
K
S
Zebra Danio
Brachydanio rerio
XP_688110
711
78788
Y382
P
E
I
M
D
R
I
Y
K
N
V
M
T
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3S9
666
73592
F368
Q
G
K
S
S
G
G
F
R
Y
K
I
A
K
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84P24
566
61938
L267
C
H
I
Y
G
L
S
L
F
V
M
G
L
L
S
Baker's Yeast
Sacchar. cerevisiae
P47912
694
77249
I375
W
E
T
V
R
K
G
I
L
A
K
I
N
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.7
98.6
93.8
N.A.
92.7
92.3
N.A.
74.1
82.2
22.3
73.6
N.A.
21.3
N.A.
N.A.
N.A.
Protein Similarity:
100
94.8
99.7
97.5
N.A.
96.5
96.2
N.A.
79.3
90.8
41.2
83.6
N.A.
40.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
100
33.3
93.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
33.3
93.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.9
28.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.4
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
16
0
0
16
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
62
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
77
0
8
0
8
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
8
8
16
0
8
0
0
16
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
70
0
0
8
62
8
0
0
0
16
0
0
0
% I
% Lys:
0
8
16
0
0
8
8
8
70
0
16
0
0
77
0
% K
% Leu:
0
0
0
0
0
8
0
8
8
0
0
0
8
16
8
% L
% Met:
0
0
8
70
0
0
0
8
0
0
8
62
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
62
0
0
62
0
0
% N
% Pro:
62
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
8
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
62
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
8
0
16
0
0
0
8
0
0
0
24
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
8
8
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
8
70
0
0
0
62
% V
% Trp:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
0
0
62
0
16
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _