KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
H6PD
All Species:
19.7
Human Site:
Y446
Identified Species:
36.11
UniProt:
O95479
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95479
NP_004276.2
791
88893
Y446
F
G
S
P
L
S
D
Y
Y
A
Y
S
P
V
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099298
791
88822
Y446
F
G
S
P
L
S
D
Y
Y
A
Y
S
P
V
Q
Dog
Lupus familis
XP_546762
789
89091
Y444
F
G
R
P
I
S
D
Y
Y
V
Y
S
P
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFX1
789
88892
Y444
F
G
R
P
L
S
D
Y
Y
A
Y
R
P
V
R
Rat
Rattus norvegicus
P05370
515
59357
D194
I
S
S
L
F
R
E
D
Q
I
Y
R
I
D
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513087
312
34898
Chicken
Gallus gallus
XP_425746
782
88274
Y439
F
G
Q
L
L
S
D
Y
Y
M
Y
S
P
V
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697820
781
88168
Y440
L
G
L
P
L
S
D
Y
Y
I
Q
S
P
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P12646
524
60412
I203
Q
E
D
Q
L
Y
R
I
D
H
Y
L
G
K
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27464
522
60197
Q201
A
K
L
F
K
E
D
Q
I
Y
R
I
D
H
Y
Sea Urchin
Strong. purpuratus
XP_795087
853
96259
F505
L
G
S
P
V
K
D
F
Y
A
Y
S
A
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150684
507
57610
S186
L
D
S
A
E
E
L
S
A
Q
L
G
E
L
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11412
505
57503
R184
F
K
E
E
E
L
Y
R
I
D
H
Y
L
G
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.4
84.8
N.A.
83.4
23.1
N.A.
30.5
69.2
N.A.
53
N.A.
22.1
N.A.
22.8
39.9
Protein Similarity:
100
N.A.
98.4
91.6
N.A.
90.3
38.4
N.A.
35.4
82.3
N.A.
71.8
N.A.
37.9
N.A.
39.3
55.9
P-Site Identity:
100
N.A.
93.3
80
N.A.
86.6
13.3
N.A.
0
73.3
N.A.
66.6
N.A.
13.3
N.A.
6.6
53.3
P-Site Similarity:
100
N.A.
100
86.6
N.A.
86.6
20
N.A.
0
80
N.A.
66.6
N.A.
13.3
N.A.
6.6
66.6
Percent
Protein Identity:
N.A.
25.2
N.A.
N.A.
22.6
N.A.
Protein Similarity:
N.A.
39.7
N.A.
N.A.
36.7
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
0
8
31
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
0
62
8
8
8
0
0
8
8
0
% D
% Glu:
0
8
8
8
16
16
8
0
0
0
0
0
8
0
8
% E
% Phe:
47
0
0
8
8
0
0
8
0
0
0
0
0
0
8
% F
% Gly:
0
54
0
0
0
0
0
0
0
0
0
8
8
16
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
8
0
0
8
8
% H
% Ile:
8
0
0
0
8
0
0
8
16
16
0
8
8
0
0
% I
% Lys:
0
16
0
0
8
8
0
0
0
0
0
0
0
8
16
% K
% Leu:
24
0
16
16
47
8
8
0
0
0
8
8
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
47
0
0
0
0
0
0
0
0
47
0
0
% P
% Gln:
8
0
8
8
0
0
0
8
8
8
8
0
0
0
8
% Q
% Arg:
0
0
16
0
0
8
8
8
0
0
8
16
0
0
24
% R
% Ser:
0
8
39
0
0
47
0
8
0
0
0
47
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
8
0
0
0
47
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
47
54
8
62
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _