KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
H6PD
All Species:
26.36
Human Site:
Y257
Identified Species:
48.33
UniProt:
O95479
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95479
NP_004276.2
791
88893
Y257
R
T
S
F
Y
E
E
Y
G
V
I
R
D
V
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099298
791
88822
Y257
R
T
S
F
Y
E
E
Y
G
V
I
R
D
V
L
Dog
Lupus familis
XP_546762
789
89091
Y254
R
T
S
F
Y
E
E
Y
G
V
I
R
D
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFX1
789
88892
Y254
R
A
S
F
Y
E
E
Y
G
V
I
R
D
T
L
Rat
Rattus norvegicus
P05370
515
59357
Q22
I
L
R
E
E
L
Y
Q
G
D
A
F
H
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513087
312
34898
Chicken
Gallus gallus
XP_425746
782
88274
Y249
R
T
S
F
Y
E
Q
Y
G
V
I
R
D
V
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697820
781
88168
Y254
R
I
Q
F
Y
D
Q
Y
G
V
I
R
D
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P12646
524
60412
D31
V
C
E
G
T
H
F
D
G
K
I
P
H
T
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27464
522
60197
L28
R
E
S
M
Q
R
D
L
K
F
E
T
P
Y
V
Sea Urchin
Strong. purpuratus
XP_795087
853
96259
Y319
R
I
Y
F
Y
D
K
Y
G
V
M
R
D
V
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150684
507
57610
F14
P
S
S
R
R
N
S
F
N
S
L
S
K
D
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11412
505
57503
T12
P
V
K
F
E
K
N
T
V
I
S
V
F
G
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.4
84.8
N.A.
83.4
23.1
N.A.
30.5
69.2
N.A.
53
N.A.
22.1
N.A.
22.8
39.9
Protein Similarity:
100
N.A.
98.4
91.6
N.A.
90.3
38.4
N.A.
35.4
82.3
N.A.
71.8
N.A.
37.9
N.A.
39.3
55.9
P-Site Identity:
100
N.A.
100
100
N.A.
86.6
6.6
N.A.
0
93.3
N.A.
73.3
N.A.
13.3
N.A.
13.3
60
P-Site Similarity:
100
N.A.
100
100
N.A.
86.6
6.6
N.A.
0
100
N.A.
86.6
N.A.
13.3
N.A.
26.6
86.6
Percent
Protein Identity:
N.A.
25.2
N.A.
N.A.
22.6
N.A.
Protein Similarity:
N.A.
39.7
N.A.
N.A.
36.7
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
16
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
16
8
8
0
8
0
0
54
8
0
% D
% Glu:
0
8
8
8
16
39
31
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
62
0
0
8
8
0
8
0
8
8
0
8
% F
% Gly:
0
0
0
8
0
0
0
0
70
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
16
0
0
% H
% Ile:
8
16
0
0
0
0
0
0
0
8
54
0
0
0
0
% I
% Lys:
0
0
8
0
0
8
8
0
8
8
0
0
8
0
0
% K
% Leu:
0
8
0
0
0
8
0
8
0
0
8
0
0
0
54
% L
% Met:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
8
% M
% Asn:
0
0
0
0
0
8
8
0
8
0
0
0
0
0
0
% N
% Pro:
16
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% P
% Gln:
0
0
8
0
8
0
16
8
0
0
0
0
0
8
0
% Q
% Arg:
62
0
8
8
8
8
0
0
0
0
0
54
0
0
0
% R
% Ser:
0
8
54
0
0
0
8
0
0
8
8
8
0
0
0
% S
% Thr:
0
31
0
0
8
0
0
8
0
0
0
8
0
16
0
% T
% Val:
8
8
0
0
0
0
0
0
8
54
0
8
0
47
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
54
0
8
54
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _