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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
H6PD
All Species:
21.82
Human Site:
S701
Identified Species:
40
UniProt:
O95479
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95479
NP_004276.2
791
88893
S701
G
A
D
G
H
T
A
S
L
F
P
Q
S
P
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099298
791
88822
S701
G
A
D
G
H
T
A
S
L
F
P
Q
S
P
T
Dog
Lupus familis
XP_546762
789
89091
S699
G
T
D
G
H
T
A
S
L
F
P
Q
S
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFX1
789
88892
S699
G
T
D
G
H
T
A
S
L
F
P
Q
S
P
T
Rat
Rattus norvegicus
P05370
515
59357
P434
R
Y
K
N
V
K
L
P
D
A
Y
E
R
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513087
312
34898
H231
D
P
I
W
N
R
H
H
V
D
R
V
E
I
V
Chicken
Gallus gallus
XP_425746
782
88274
S692
G
T
D
G
H
T
A
S
L
F
P
H
S
E
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697820
781
88168
S691
G
Q
D
G
H
T
A
S
L
F
Q
D
T
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P12646
524
60412
E443
S
Y
L
P
D
A
Y
E
R
L
I
L
D
V
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27464
522
60197
L441
N
R
F
K
E
V
R
L
P
D
A
Y
E
R
L
Sea Urchin
Strong. purpuratus
XP_795087
853
96259
S761
G
E
D
G
H
V
A
S
L
F
P
H
H
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150684
507
57610
P426
R
Y
Q
N
V
K
I
P
E
A
Y
E
R
L
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11412
505
57503
R424
E
A
Y
E
V
L
I
R
D
A
L
L
G
D
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.4
84.8
N.A.
83.4
23.1
N.A.
30.5
69.2
N.A.
53
N.A.
22.1
N.A.
22.8
39.9
Protein Similarity:
100
N.A.
98.4
91.6
N.A.
90.3
38.4
N.A.
35.4
82.3
N.A.
71.8
N.A.
37.9
N.A.
39.3
55.9
P-Site Identity:
100
N.A.
100
86.6
N.A.
93.3
0
N.A.
0
73.3
N.A.
60
N.A.
0
N.A.
0
60
P-Site Similarity:
100
N.A.
100
86.6
N.A.
93.3
6.6
N.A.
13.3
73.3
N.A.
66.6
N.A.
0
N.A.
0
60
Percent
Protein Identity:
N.A.
25.2
N.A.
N.A.
22.6
N.A.
Protein Similarity:
N.A.
39.7
N.A.
N.A.
36.7
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
0
0
0
8
54
0
0
24
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
54
0
8
0
0
0
16
16
0
8
8
8
0
% D
% Glu:
8
8
0
8
8
0
0
8
8
0
0
16
16
16
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
54
0
0
0
0
8
% F
% Gly:
54
0
0
54
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
54
0
8
8
0
0
0
16
8
0
8
% H
% Ile:
0
0
8
0
0
0
16
0
0
0
8
0
0
8
24
% I
% Lys:
0
0
8
8
0
16
0
0
0
0
0
0
0
8
0
% K
% Leu:
0
0
8
0
0
8
8
8
54
8
8
16
0
16
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
16
8
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
8
0
8
0
0
0
16
8
0
47
0
0
31
0
% P
% Gln:
0
8
8
0
0
0
0
0
0
0
8
31
0
0
0
% Q
% Arg:
16
8
0
0
0
8
8
8
8
0
8
0
16
8
0
% R
% Ser:
8
0
0
0
0
0
0
54
0
0
0
0
39
0
0
% S
% Thr:
0
24
0
0
0
47
0
0
0
0
0
0
8
0
24
% T
% Val:
0
0
0
0
24
16
0
0
8
0
0
8
0
8
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
24
8
0
0
0
8
0
0
0
16
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _