KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
H6PD
All Species:
21.82
Human Site:
S631
Identified Species:
40
UniProt:
O95479
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95479
NP_004276.2
791
88893
S631
V
P
L
S
D
P
E
S
N
F
Q
G
L
Q
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099298
791
88822
S631
V
P
L
S
D
P
E
S
N
F
Q
G
L
Q
A
Dog
Lupus familis
XP_546762
789
89091
S629
V
P
L
W
D
P
E
S
N
F
Q
G
L
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFX1
789
88892
S629
V
P
L
S
D
P
D
S
N
F
Q
G
L
Q
A
Rat
Rattus norvegicus
P05370
515
59357
D375
E
V
R
L
Q
F
R
D
V
A
G
D
I
F
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513087
312
34898
K172
W
L
R
V
V
L
E
K
P
F
G
H
D
Y
Q
Chicken
Gallus gallus
XP_425746
782
88274
S622
V
P
L
T
D
P
E
S
N
F
F
S
L
H
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697820
781
88168
S621
V
P
H
T
E
S
G
S
N
F
R
S
I
H
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P12646
524
60412
D384
Q
Y
Q
D
V
L
G
D
I
F
E
G
N
T
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27464
522
60197
E382
E
V
R
I
Q
F
K
E
V
S
G
D
I
Y
P
Sea Urchin
Strong. purpuratus
XP_795087
853
96259
S691
V
P
L
D
S
E
L
S
N
F
N
V
I
Y
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150684
507
57610
V367
V
R
V
Q
F
K
D
V
P
G
D
I
F
R
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11412
505
57503
K365
A
V
A
S
G
V
F
K
D
I
P
N
N
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.4
84.8
N.A.
83.4
23.1
N.A.
30.5
69.2
N.A.
53
N.A.
22.1
N.A.
22.8
39.9
Protein Similarity:
100
N.A.
98.4
91.6
N.A.
90.3
38.4
N.A.
35.4
82.3
N.A.
71.8
N.A.
37.9
N.A.
39.3
55.9
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
0
N.A.
13.3
66.6
N.A.
33.3
N.A.
13.3
N.A.
0
40
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
6.6
N.A.
13.3
73.3
N.A.
60
N.A.
20
N.A.
13.3
53.3
Percent
Protein Identity:
N.A.
25.2
N.A.
N.A.
22.6
N.A.
Protein Similarity:
N.A.
39.7
N.A.
N.A.
36.7
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
0
0
8
0
0
0
0
31
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
16
39
0
16
16
8
0
8
16
8
0
8
% D
% Glu:
16
0
0
0
8
8
39
8
0
0
8
0
0
8
0
% E
% Phe:
0
0
0
0
8
16
8
0
0
70
8
0
8
8
0
% F
% Gly:
0
0
0
0
8
0
16
0
0
8
24
39
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
8
0
16
8
% H
% Ile:
0
0
0
8
0
0
0
0
8
8
0
8
31
0
0
% I
% Lys:
0
0
0
0
0
8
8
16
0
0
0
0
0
0
8
% K
% Leu:
0
8
47
8
0
16
8
0
0
0
0
0
39
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
54
0
8
8
16
0
8
% N
% Pro:
0
54
0
0
0
39
0
0
16
0
8
0
0
0
8
% P
% Gln:
8
0
8
8
16
0
0
0
0
0
31
0
0
31
8
% Q
% Arg:
0
8
24
0
0
0
8
0
0
0
8
0
0
8
0
% R
% Ser:
0
0
0
31
8
8
0
54
0
8
0
16
0
0
16
% S
% Thr:
0
0
0
16
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
62
24
8
8
16
8
0
8
16
0
0
8
0
0
0
% V
% Trp:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
24
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _