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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
H6PD
All Species:
15.15
Human Site:
S541
Identified Species:
27.78
UniProt:
O95479
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95479
NP_004276.2
791
88893
S541
P
G
P
A
P
M
P
S
D
F
Q
V
L
R
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099298
791
88822
S541
P
G
P
A
P
M
P
S
D
F
Q
V
L
R
A
Dog
Lupus familis
XP_546762
789
89091
S539
P
G
S
A
P
M
P
S
N
F
Q
V
L
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFX1
789
88892
S539
L
G
S
V
P
K
P
S
D
F
Q
V
L
G
A
Rat
Rattus norvegicus
P05370
515
59357
D286
T
D
S
D
D
V
R
D
E
K
V
K
V
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513087
312
34898
S83
A
E
A
L
K
R
L
S
C
P
A
D
V
A
P
Chicken
Gallus gallus
XP_425746
782
88274
S532
N
P
S
G
P
M
P
S
D
Y
K
T
I
Q
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697820
781
88168
N532
I
N
R
G
A
E
E
N
F
Q
V
M
Q
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P12646
524
60412
V295
I
R
D
E
K
V
K
V
L
K
S
I
E
A
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27464
522
60197
E293
N
A
E
D
I
R
D
E
K
V
K
V
L
K
A
Sea Urchin
Strong. purpuratus
XP_795087
853
96259
P600
D
S
N
R
F
G
M
P
S
I
S
G
I
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150684
507
57610
P278
C
L
V
A
M
E
K
P
V
S
L
K
P
E
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11412
505
57503
K276
S
I
R
D
E
K
V
K
V
L
K
A
V
A
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.4
84.8
N.A.
83.4
23.1
N.A.
30.5
69.2
N.A.
53
N.A.
22.1
N.A.
22.8
39.9
Protein Similarity:
100
N.A.
98.4
91.6
N.A.
90.3
38.4
N.A.
35.4
82.3
N.A.
71.8
N.A.
37.9
N.A.
39.3
55.9
P-Site Identity:
100
N.A.
100
80
N.A.
66.6
0
N.A.
6.6
33.3
N.A.
0
N.A.
0
N.A.
20
0
P-Site Similarity:
100
N.A.
100
86.6
N.A.
66.6
20
N.A.
13.3
66.6
N.A.
13.3
N.A.
13.3
N.A.
33.3
6.6
Percent
Protein Identity:
N.A.
25.2
N.A.
N.A.
22.6
N.A.
Protein Similarity:
N.A.
39.7
N.A.
N.A.
36.7
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
31
8
0
0
0
0
0
8
8
0
24
39
% A
% Cys:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
8
8
24
8
0
8
8
31
0
0
8
0
0
8
% D
% Glu:
0
8
8
8
8
16
8
8
8
0
0
0
8
8
0
% E
% Phe:
0
0
0
0
8
0
0
0
8
31
0
0
0
0
0
% F
% Gly:
0
31
0
16
0
8
0
0
0
0
0
8
0
16
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
16
8
0
0
8
0
0
0
0
8
0
8
16
0
0
% I
% Lys:
0
0
0
0
16
16
16
8
8
16
24
16
0
8
16
% K
% Leu:
8
8
0
8
0
0
8
0
8
8
8
0
39
8
8
% L
% Met:
0
0
0
0
8
31
8
0
0
0
0
8
0
0
0
% M
% Asn:
16
8
8
0
0
0
0
8
8
0
0
0
0
0
0
% N
% Pro:
24
8
16
0
39
0
39
16
0
8
0
0
8
8
16
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
31
0
8
8
0
% Q
% Arg:
0
8
16
8
0
16
8
0
0
0
0
0
0
16
0
% R
% Ser:
8
8
31
0
0
0
0
47
8
8
16
0
0
0
8
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% T
% Val:
0
0
8
8
0
16
8
8
16
8
16
39
24
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _