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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
H6PD
All Species:
20
Human Site:
S332
Identified Species:
36.67
UniProt:
O95479
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95479
NP_004276.2
791
88893
S332
Q
K
P
D
S
F
H
S
L
T
P
T
F
A
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099298
791
88822
S332
Q
K
P
D
S
F
H
S
L
T
P
T
F
A
A
Dog
Lupus familis
XP_546762
789
89091
S329
Q
K
P
D
S
F
Y
S
L
T
P
T
F
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFX1
789
88892
S329
Q
K
P
D
G
F
Q
S
L
T
P
T
F
A
G
Rat
Rattus norvegicus
P05370
515
59357
V90
Q
S
E
P
F
F
K
V
T
P
E
E
R
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513087
312
34898
Chicken
Gallus gallus
XP_425746
782
88274
S324
Q
K
G
Q
D
Y
V
S
T
T
P
T
F
A
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697820
781
88168
S329
N
K
T
K
D
Y
F
S
L
T
P
T
F
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P12646
524
60412
Q99
M
K
V
Q
P
H
E
Q
K
K
Y
E
E
F
W
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27464
522
60197
E96
N
C
K
V
R
E
N
E
K
C
A
F
D
D
F
Sea Urchin
Strong. purpuratus
XP_795087
853
96259
S394
D
K
G
E
D
D
T
S
S
V
P
T
F
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150684
507
57610
R82
S
D
D
G
L
R
E
R
I
R
G
Y
L
K
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11412
505
57503
K80
H
G
E
A
D
D
S
K
V
E
Q
F
F
K
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.4
84.8
N.A.
83.4
23.1
N.A.
30.5
69.2
N.A.
53
N.A.
22.1
N.A.
22.8
39.9
Protein Similarity:
100
N.A.
98.4
91.6
N.A.
90.3
38.4
N.A.
35.4
82.3
N.A.
71.8
N.A.
37.9
N.A.
39.3
55.9
P-Site Identity:
100
N.A.
100
86.6
N.A.
80
13.3
N.A.
0
53.3
N.A.
53.3
N.A.
6.6
N.A.
0
40
P-Site Similarity:
100
N.A.
100
93.3
N.A.
80
13.3
N.A.
0
60
N.A.
60
N.A.
6.6
N.A.
6.6
46.6
Percent
Protein Identity:
N.A.
25.2
N.A.
N.A.
22.6
N.A.
Protein Similarity:
N.A.
39.7
N.A.
N.A.
36.7
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
8
0
0
54
16
% A
% Cys:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
8
8
31
31
16
0
0
0
0
0
0
8
8
0
% D
% Glu:
0
0
16
8
0
8
16
8
0
8
8
16
8
0
0
% E
% Phe:
0
0
0
0
8
39
8
0
0
0
0
16
62
8
8
% F
% Gly:
0
8
16
8
8
0
0
0
0
0
8
0
0
0
47
% G
% His:
8
0
0
0
0
8
16
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
62
8
8
0
0
8
8
16
8
0
0
0
16
8
% K
% Leu:
0
0
0
0
8
0
0
0
39
0
0
0
8
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
16
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
31
8
8
0
0
0
0
8
54
0
0
8
0
% P
% Gln:
47
0
0
16
0
0
8
8
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
8
8
0
8
0
8
0
0
8
0
0
% R
% Ser:
8
8
0
0
24
0
8
54
8
0
0
0
0
0
0
% S
% Thr:
0
0
8
0
0
0
8
0
16
47
0
54
0
0
0
% T
% Val:
0
0
8
8
0
0
8
8
8
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
16
8
0
0
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _