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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DULLARD All Species: 42.42
Human Site: S173 Identified Species: 66.67
UniProt: O95476 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95476 NP_001137247.1 244 28377 S173 G S Y I K D L S V V H S D L S
Chimpanzee Pan troglodytes XP_511976 360 39659 S290 G S Y I K D L S V V H S D L S
Rhesus Macaque Macaca mulatta XP_001117997 321 36189 S172 G S Y I K D L S V V H S D L S
Dog Lupus familis XP_848951 244 28345 S173 G S Y I K D L S V V H S D L S
Cat Felis silvestris
Mouse Mus musculus Q3TP92 244 28373 S173 G S Y I K D L S V V H S D L S
Rat Rattus norvegicus Q5XIK8 465 52764 N390 G N Y I K D L N I L G R D L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9PTJ6 275 31225 N202 S C V F H R G N Y V K D L S R
Frog Xenopus laevis Q8JIL9 244 28150 S173 G S Y I K D L S V V H S D L S
Zebra Danio Brachydanio rerio Q5U395 245 28489 S174 G S Y I K D L S V V H S D L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRG7 243 28468 S172 G S Y T K D L S A I C S D L N
Honey Bee Apis mellifera XP_391964 243 28124 S172 G S Y T K D L S A I C S D L A
Nematode Worm Caenorhab. elegans Q20432 246 28395 S169 G G Y T K D L S A I H P D L S
Sea Urchin Strong. purpuratus XP_001189064 192 21745 S123 S A V H P D L S S I F I V D N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VYE2 376 42621 S278 G K H Y R D L S K L N R D P K
Baker's Yeast Sacchar. cerevisiae P38757 446 50623 K373 K D S E E N G K G S S S S L D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67.5 74.7 99.5 N.A. 99.5 23.2 N.A. N.A. 29.4 92.6 90.1 N.A. 69.2 72.9 65.4 52.8
Protein Similarity: 100 67.5 75.3 99.5 N.A. 100 36.1 N.A. N.A. 51.6 97.1 96.7 N.A. 82.7 87.3 78.8 60.6
P-Site Identity: 100 100 100 100 N.A. 100 60 N.A. N.A. 6.6 100 100 N.A. 66.6 66.6 66.6 20
P-Site Similarity: 100 100 100 100 N.A. 100 86.6 N.A. N.A. 13.3 100 100 N.A. 80 80 73.3 40
Percent
Protein Identity: N.A. N.A. N.A. 21.5 24.8 N.A.
Protein Similarity: N.A. N.A. N.A. 36.1 39.9 N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 0 0 20 0 0 0 0 0 7 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 14 0 0 0 0 % C
% Asp: 0 7 0 0 0 87 0 0 0 0 0 7 80 7 7 % D
% Glu: 0 0 0 7 7 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 7 0 0 0 0 0 0 7 0 0 0 0 % F
% Gly: 80 7 0 0 0 0 14 0 7 0 7 0 0 0 0 % G
% His: 0 0 7 7 7 0 0 0 0 0 54 0 0 0 0 % H
% Ile: 0 0 0 54 0 0 0 0 7 27 0 7 0 0 0 % I
% Lys: 7 7 0 0 74 0 0 7 7 0 7 0 0 0 7 % K
% Leu: 0 0 0 0 0 0 87 0 0 14 0 0 7 80 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 7 0 14 0 0 7 0 0 0 14 % N
% Pro: 0 0 0 0 7 0 0 0 0 0 0 7 0 7 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 7 7 0 0 0 0 0 14 0 0 7 % R
% Ser: 14 60 7 0 0 0 0 80 7 7 7 67 7 7 60 % S
% Thr: 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 14 0 0 0 0 0 47 54 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 74 7 0 0 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _