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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DULLARD All Species: 33.33
Human Site: S139 Identified Species: 52.38
UniProt: O95476 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95476 NP_001137247.1 244 28377 S139 A S M E I Y G S A V A D K L D
Chimpanzee Pan troglodytes XP_511976 360 39659 S256 A S M E I Y G S A V A D K L D
Rhesus Macaque Macaca mulatta XP_001117997 321 36189 S138 A S M E I Y G S A V A D K L D
Dog Lupus familis XP_848951 244 28345 S139 A S M E I Y G S A V A D K L D
Cat Felis silvestris
Mouse Mus musculus Q3TP92 244 28373 S139 A S M E I Y G S A V A D K L D
Rat Rattus norvegicus Q5XIK8 465 52764 D356 A S K K V Y A D K L L N I L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9PTJ6 275 31225 A168 F E C V L F T A S L A K Y A D
Frog Xenopus laevis Q8JIL9 244 28150 S139 A S M E I Y G S A V A D K L D
Zebra Danio Brachydanio rerio Q5U395 245 28489 S140 A S M E I Y G S A V A D K L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VRG7 243 28468 A138 A S M E I Y G A A V A D K L D
Honey Bee Apis mellifera XP_391964 243 28124 A138 A S M E I Y G A A V A E K L D
Nematode Worm Caenorhab. elegans Q20432 246 28395 T135 A S M E V Y G T S V A D R L D
Sea Urchin Strong. purpuratus XP_001189064 192 21745 D89 S P V V E K L D N G R G L L Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VYE2 376 42621 V244 S D Q M E M Y V L P V C E K L
Baker's Yeast Sacchar. cerevisiae P38757 446 50623 S339 W L E S S F P S S F S K R Y Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67.5 74.7 99.5 N.A. 99.5 23.2 N.A. N.A. 29.4 92.6 90.1 N.A. 69.2 72.9 65.4 52.8
Protein Similarity: 100 67.5 75.3 99.5 N.A. 100 36.1 N.A. N.A. 51.6 97.1 96.7 N.A. 82.7 87.3 78.8 60.6
P-Site Identity: 100 100 100 100 N.A. 100 33.3 N.A. N.A. 13.3 100 100 N.A. 93.3 86.6 73.3 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 60 N.A. N.A. 46.6 100 100 N.A. 100 100 100 20
Percent
Protein Identity: N.A. N.A. N.A. 21.5 24.8 N.A.
Protein Similarity: N.A. N.A. N.A. 36.1 39.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 74 0 0 0 0 0 7 20 60 0 74 0 0 7 0 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 7 0 0 0 % C
% Asp: 0 7 0 0 0 0 0 14 0 0 0 60 0 0 80 % D
% Glu: 0 7 7 67 14 0 0 0 0 0 0 7 7 0 0 % E
% Phe: 7 0 0 0 0 14 0 0 0 7 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 67 0 0 7 0 7 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 60 0 0 0 0 0 0 0 7 0 0 % I
% Lys: 0 0 7 7 0 7 0 0 7 0 0 14 60 7 0 % K
% Leu: 0 7 0 0 7 0 7 0 7 14 7 0 7 80 7 % L
% Met: 0 0 67 7 0 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 7 0 0 7 0 0 0 % N
% Pro: 0 7 0 0 0 0 7 0 0 7 0 0 0 0 0 % P
% Gln: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 7 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 7 0 14 0 0 % R
% Ser: 14 74 0 7 7 0 0 54 20 0 7 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 7 7 0 0 0 0 0 0 0 % T
% Val: 0 0 7 14 14 0 0 7 0 67 7 0 0 0 0 % V
% Trp: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 74 7 0 0 0 0 0 7 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _