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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIX6
All Species:
52.12
Human Site:
Y152
Identified Species:
95.56
UniProt:
O95475
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95475
NP_031400.2
246
27687
Y152
E
W
Y
L
Q
D
P
Y
P
N
P
S
K
K
R
Chimpanzee
Pan troglodytes
XP_522870
514
56142
Y420
E
W
Y
L
Q
D
P
Y
P
N
P
S
K
K
R
Rhesus Macaque
Macaca mulatta
XP_001094228
396
43626
Y302
E
W
Y
L
Q
D
P
Y
P
N
P
S
K
K
R
Dog
Lupus familis
XP_547840
343
38064
Y249
E
W
Y
L
Q
D
P
Y
P
N
P
S
K
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZ28
246
27723
Y152
E
W
Y
L
Q
D
P
Y
P
N
P
S
K
K
R
Rat
Rattus norvegicus
NP_076480
337
35742
Y235
E
W
Y
L
Q
D
P
Y
P
N
P
S
K
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O93307
246
27619
Y152
E
W
Y
L
Q
D
P
Y
P
N
P
S
K
K
R
Frog
Xenopus laevis
P79937
390
42868
Y299
F
Q
H
L
T
H
P
Y
P
S
E
E
Q
K
K
Zebra Danio
Brachydanio rerio
NP_957399
245
27632
Y152
E
W
Y
L
Q
D
P
Y
P
N
P
S
K
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95RW8
487
52401
Y180
E
W
Y
L
Q
D
P
Y
P
N
P
T
K
K
R
Honey Bee
Apis mellifera
XP_623764
475
51466
Y177
E
W
Y
L
Q
D
P
Y
P
N
P
G
K
K
R
Nematode Worm
Caenorhab. elegans
Q23175
439
49618
Y209
E
W
Y
L
K
D
P
Y
P
N
P
P
K
K
K
Sea Urchin
Strong. purpuratus
XP_781696
324
36468
Y217
E
W
Y
L
Q
D
P
Y
P
N
P
T
K
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.8
61.3
70.5
N.A.
97.9
59
N.A.
N.A.
93.5
20.2
90.6
N.A.
39.2
41.2
35
57.4
Protein Similarity:
100
47.8
61.3
70.8
N.A.
99.1
65.5
N.A.
N.A.
95.9
33.3
94.3
N.A.
43.7
45.4
42.1
63.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
33.3
100
N.A.
93.3
93.3
80
93.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
60
100
N.A.
100
93.3
93.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
93
0
0
0
0
0
0
0
0
0
% D
% Glu:
93
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
0
0
0
93
100
16
% K
% Leu:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
93
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
100
0
100
0
93
8
0
0
0
% P
% Gln:
0
8
0
0
85
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
85
% R
% Ser:
0
0
0
0
0
0
0
0
0
8
0
62
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
0
0
0
0
16
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
93
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
93
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _