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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGPL1
All Species:
41.52
Human Site:
T426
Identified Species:
57.08
UniProt:
O95470
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95470
NP_003892.2
568
63524
T426
A
T
K
Q
I
I
K
T
A
R
F
L
K
S
E
Chimpanzee
Pan troglodytes
XP_521504
568
63517
T426
A
T
K
Q
I
I
K
T
A
R
F
L
K
S
E
Rhesus Macaque
Macaca mulatta
XP_001106861
633
70448
T491
A
T
K
Q
I
I
K
T
A
R
F
L
K
S
E
Dog
Lupus familis
XP_546150
568
63418
T426
A
T
K
Q
I
I
K
T
T
R
F
L
K
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0X7
568
63659
T426
A
T
K
Q
I
I
K
T
A
R
F
L
K
S
E
Rat
Rattus norvegicus
Q8CHN6
568
63740
T426
A
T
K
Q
I
I
K
T
A
R
F
L
K
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508856
560
61966
T418
A
T
K
K
I
I
K
T
A
R
Y
L
K
S
E
Chicken
Gallus gallus
NP_001007947
561
62425
T419
A
T
K
R
I
I
K
T
A
R
F
L
E
S
E
Frog
Xenopus laevis
NP_001091225
453
50814
Y316
V
A
K
L
A
L
K
Y
Q
L
P
F
H
V
D
Zebra Danio
Brachydanio rerio
NP_001082938
572
63710
T422
A
T
R
K
V
V
E
T
T
R
K
I
K
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7Y2
545
60287
T409
Y
D
G
Y
L
E
A
T
K
R
I
V
D
T
A
Honey Bee
Apis mellifera
XP_623988
549
61593
T411
S
T
K
K
I
I
K
T
T
R
Y
I
E
Q
R
Nematode Worm
Caenorhab. elegans
Q9Y194
552
61079
A415
D
E
Y
V
R
R
C
A
Q
I
V
K
H
T
R
Sea Urchin
Strong. purpuratus
XP_790556
422
46078
R287
D
G
Y
V
E
N
T
R
K
I
V
S
T
T
R
Poplar Tree
Populus trichocarpa
XP_002304674
540
58782
L405
A
A
L
M
A
L
G
L
E
G
Y
L
E
N
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C509
544
59459
E409
A
A
M
M
S
L
G
E
E
G
Y
L
Q
N
T
Baker's Yeast
Sacchar. cerevisiae
Q05567
589
65547
A453
S
C
Q
E
I
V
G
A
A
M
K
F
K
K
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
89.2
93.3
N.A.
84.6
85.5
N.A.
77.2
68.4
51.4
63.4
N.A.
46.4
48.2
41
44.3
Protein Similarity:
100
99.8
89.5
96.6
N.A.
92
91.7
N.A.
85.9
81.3
63.3
79.7
N.A.
64.7
66.5
58.7
57.9
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
86.6
86.6
13.3
33.3
N.A.
13.3
46.6
0
0
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
100
100
26.6
80
N.A.
33.3
80
6.6
6.6
Percent
Protein Identity:
41.9
N.A.
N.A.
40.6
37
N.A.
Protein Similarity:
58.9
N.A.
N.A.
59.1
57
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
40
N.A.
N.A.
40
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
65
18
0
0
12
0
6
12
48
0
0
0
0
0
6
% A
% Cys:
0
6
0
0
0
0
6
0
0
0
0
0
0
0
0
% C
% Asp:
12
6
0
0
0
0
0
0
0
0
0
0
6
0
6
% D
% Glu:
0
6
0
6
6
6
6
6
12
0
0
0
18
0
48
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
42
12
0
0
0
% F
% Gly:
0
6
6
0
0
0
18
0
0
12
0
0
0
0
6
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% H
% Ile:
0
0
0
0
59
53
0
0
0
12
6
12
0
0
0
% I
% Lys:
0
0
59
18
0
0
59
0
12
0
12
6
53
6
0
% K
% Leu:
0
0
6
6
6
18
0
6
0
6
0
59
0
0
0
% L
% Met:
0
0
6
12
0
0
0
0
0
6
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
6
0
0
0
0
0
0
0
12
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% P
% Gln:
0
0
6
36
0
0
0
0
12
0
0
0
6
6
0
% Q
% Arg:
0
0
6
6
6
6
0
6
0
65
0
0
0
0
18
% R
% Ser:
12
0
0
0
6
0
0
0
0
0
0
6
0
48
0
% S
% Thr:
0
59
0
0
0
0
6
65
18
0
0
0
6
24
12
% T
% Val:
6
0
0
12
6
12
0
0
0
0
12
6
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
12
6
0
0
0
6
0
0
24
0
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _