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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGPL1
All Species:
13.64
Human Site:
S118
Identified Species:
18.75
UniProt:
O95470
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95470
NP_003892.2
568
63524
S118
E
Y
V
K
A
L
P
S
Q
G
L
S
S
S
A
Chimpanzee
Pan troglodytes
XP_521504
568
63517
S118
E
Y
V
K
A
L
P
S
Q
G
L
S
S
S
A
Rhesus Macaque
Macaca mulatta
XP_001106861
633
70448
T183
E
Y
V
K
A
L
P
T
Q
G
L
S
S
S
A
Dog
Lupus familis
XP_546150
568
63418
S118
E
Y
V
K
A
L
P
S
Q
G
L
S
A
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0X7
568
63659
A118
D
Y
V
K
T
L
P
A
Q
G
M
G
T
A
E
Rat
Rattus norvegicus
Q8CHN6
568
63740
A118
D
Y
V
K
T
L
P
A
Q
G
L
S
T
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508856
560
61966
L118
G
L
N
Q
S
D
V
L
D
R
L
R
E
Y
S
Chicken
Gallus gallus
NP_001007947
561
62425
L119
G
M
S
Q
P
E
V
L
Q
K
M
K
E
Y
S
Frog
Xenopus laevis
NP_001091225
453
50814
F30
N
F
T
L
T
S
V
F
Q
L
R
N
L
I
N
Zebra Danio
Brachydanio rerio
NP_001082938
572
63710
H118
L
P
A
Q
G
L
T
H
K
Q
L
L
D
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7Y2
545
60287
L116
S
K
E
E
I
L
R
L
V
D
E
H
L
K
T
Honey Bee
Apis mellifera
XP_623988
549
61593
Q118
E
R
V
K
Q
C
V
Q
L
G
D
Y
N
W
K
Nematode Worm
Caenorhab. elegans
Q9Y194
552
61079
Q116
L
P
I
A
P
L
S
Q
D
S
I
M
E
L
A
Sea Urchin
Strong. purpuratus
XP_790556
422
46078
Poplar Tree
Populus trichocarpa
XP_002304674
540
58782
Q117
A
V
I
E
K
L
K
Q
E
K
S
N
D
V
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C509
544
59459
N121
E
V
L
E
K
M
E
N
E
K
R
N
D
A
I
Baker's Yeast
Sacchar. cerevisiae
Q05567
589
65547
G142
F
P
Q
L
P
S
N
G
I
P
Q
D
D
V
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
89.2
93.3
N.A.
84.6
85.5
N.A.
77.2
68.4
51.4
63.4
N.A.
46.4
48.2
41
44.3
Protein Similarity:
100
99.8
89.5
96.6
N.A.
92
91.7
N.A.
85.9
81.3
63.3
79.7
N.A.
64.7
66.5
58.7
57.9
P-Site Identity:
100
100
93.3
93.3
N.A.
46.6
60
N.A.
6.6
6.6
6.6
13.3
N.A.
6.6
26.6
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
80
86.6
N.A.
26.6
26.6
20
26.6
N.A.
13.3
33.3
26.6
0
Percent
Protein Identity:
41.9
N.A.
N.A.
40.6
37
N.A.
Protein Similarity:
58.9
N.A.
N.A.
59.1
57
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
53.3
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
6
6
24
0
0
12
0
0
0
0
6
18
30
% A
% Cys:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
0
6
0
0
12
6
6
6
24
0
0
% D
% Glu:
36
0
6
18
0
6
6
0
12
0
6
0
18
0
12
% E
% Phe:
6
6
0
0
0
0
0
6
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
6
0
0
6
0
42
0
6
0
0
0
% G
% His:
0
0
0
0
0
0
0
6
0
0
0
6
0
0
0
% H
% Ile:
0
0
12
0
6
0
0
0
6
0
6
0
0
6
18
% I
% Lys:
0
6
0
42
12
0
6
0
6
18
0
6
0
12
6
% K
% Leu:
12
6
6
12
0
59
0
18
6
6
42
6
12
6
0
% L
% Met:
0
6
0
0
0
6
0
0
0
0
12
6
0
0
0
% M
% Asn:
6
0
6
0
0
0
6
6
0
0
0
18
6
0
6
% N
% Pro:
0
18
0
0
18
0
36
0
0
6
0
0
0
0
0
% P
% Gln:
0
0
6
18
6
0
0
18
48
6
6
0
0
0
0
% Q
% Arg:
0
6
0
0
0
0
6
0
0
6
12
6
0
0
0
% R
% Ser:
6
0
6
0
6
12
6
18
0
6
6
30
18
24
12
% S
% Thr:
0
0
6
0
18
0
6
6
0
0
0
0
12
0
6
% T
% Val:
0
12
42
0
0
0
24
0
6
0
0
0
0
12
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% W
% Tyr:
0
36
0
0
0
0
0
0
0
0
0
6
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _