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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAPLN
All Species:
8.48
Human Site:
T274
Identified Species:
20.74
UniProt:
O95428
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95428
NP_775733.3
1278
137700
T274
R
L
H
A
R
G
P
T
S
E
P
L
V
I
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088864
1244
134167
P262
L
I
S
Q
E
P
N
P
G
V
H
Y
E
Y
H
Dog
Lupus familis
XP_547891
1189
127952
D261
Q
P
Q
L
R
P
A
D
R
R
P
C
S
T
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPX2
1280
138805
T275
R
L
Q
A
R
G
P
T
S
E
P
L
V
I
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426430
1196
131476
L256
G
V
Q
Y
E
Y
Y
L
P
M
H
R
Q
T
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919035
930
101902
E9
C
K
T
V
S
E
G
E
N
P
C
E
L
N
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q868Z9
2898
313016
S308
C
S
G
P
I
S
E
S
L
F
I
V
M
L
V
Honey Bee
Apis mellifera
XP_396472
2807
307624
T296
T
I
T
A
L
G
P
T
N
E
P
I
Y
V
V
Nematode Worm
Caenorhab. elegans
O76840
2167
237582
Q555
E
V
T
C
K
D
S
Q
G
R
A
Y
P
L
E
Sea Urchin
Strong. purpuratus
XP_001182864
608
67786
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
91.8
72.1
N.A.
74.5
N.A.
N.A.
N.A.
51.2
N.A.
33.4
N.A.
20.3
20.9
22.5
21.7
Protein Similarity:
100
N.A.
93
78
N.A.
82.3
N.A.
N.A.
N.A.
66.1
N.A.
45.6
N.A.
28.3
29.4
32.7
31
P-Site Identity:
100
N.A.
0
13.3
N.A.
93.3
N.A.
N.A.
N.A.
0
N.A.
0
N.A.
0
40
6.6
0
P-Site Similarity:
100
N.A.
6.6
20
N.A.
93.3
N.A.
N.A.
N.A.
6.6
N.A.
13.3
N.A.
26.6
66.6
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
30
0
0
10
0
0
0
10
0
0
0
0
% A
% Cys:
20
0
0
10
0
0
0
0
0
0
10
10
0
0
10
% C
% Asp:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
20
10
10
10
0
30
0
10
10
0
30
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
10
0
10
0
0
30
10
0
20
0
0
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
20
0
0
0
20
% H
% Ile:
0
20
0
0
10
0
0
0
0
0
10
10
0
20
0
% I
% Lys:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
20
0
10
10
0
0
10
10
0
0
20
10
20
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
20
0
0
0
0
10
0
% N
% Pro:
0
10
0
10
0
20
30
10
10
10
40
0
10
0
0
% P
% Gln:
10
0
30
10
0
0
0
10
0
0
0
0
10
0
0
% Q
% Arg:
20
0
0
0
30
0
0
0
10
20
0
10
0
0
0
% R
% Ser:
0
10
10
0
10
10
10
10
20
0
0
0
10
0
0
% S
% Thr:
10
0
30
0
0
0
0
30
0
0
0
0
0
20
10
% T
% Val:
0
20
0
10
0
0
0
0
0
10
0
10
20
10
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
10
10
0
0
0
0
20
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _