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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAPLN
All Species:
3.03
Human Site:
S689
Identified Species:
7.41
UniProt:
O95428
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95428
NP_775733.3
1278
137700
S689
T
K
S
Y
G
G
D
S
T
G
G
M
P
R
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088864
1244
134167
S655
T
K
L
Y
G
S
D
S
T
R
S
R
P
R
S
Dog
Lupus familis
XP_547891
1189
127952
Y651
V
G
Q
P
N
Y
A
Y
P
V
R
C
L
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPX2
1280
138805
N685
T
R
S
H
G
S
D
N
T
G
N
R
P
G
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426430
1196
131476
N646
S
F
N
T
C
H
Q
N
R
Y
G
C
C
P
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919035
930
101902
A398
C
H
D
G
V
T
V
A
Q
G
Q
N
M
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q868Z9
2898
313016
K1559
H
C
T
Q
T
E
F
K
C
C
D
D
E
K
T
Honey Bee
Apis mellifera
XP_396472
2807
307624
G1782
H
Q
Q
C
L
Q
P
G
R
R
R
D
S
C
L
Nematode Worm
Caenorhab. elegans
O76840
2167
237582
C1026
Q
Y
T
R
Y
G
C
C
P
D
G
E
T
T
A
Sea Urchin
Strong. purpuratus
XP_001182864
608
67786
A76
E
H
F
Y
Y
R
H
A
E
K
V
I
D
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
91.8
72.1
N.A.
74.5
N.A.
N.A.
N.A.
51.2
N.A.
33.4
N.A.
20.3
20.9
22.5
21.7
Protein Similarity:
100
N.A.
93
78
N.A.
82.3
N.A.
N.A.
N.A.
66.1
N.A.
45.6
N.A.
28.3
29.4
32.7
31
P-Site Identity:
100
N.A.
66.6
0
N.A.
53.3
N.A.
N.A.
N.A.
6.6
N.A.
6.6
N.A.
0
0
13.3
6.6
P-Site Similarity:
100
N.A.
66.6
0
N.A.
73.3
N.A.
N.A.
N.A.
26.6
N.A.
13.3
N.A.
20
6.6
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
20
0
0
0
0
0
0
10
% A
% Cys:
10
10
0
10
10
0
10
10
10
10
0
20
10
10
0
% C
% Asp:
0
0
10
0
0
0
30
0
0
10
10
20
10
0
10
% D
% Glu:
10
0
0
0
0
10
0
0
10
0
0
10
10
10
0
% E
% Phe:
0
10
10
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
10
30
20
0
10
0
30
30
0
0
20
10
% G
% His:
20
20
0
10
0
10
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
20
0
0
0
0
0
10
0
10
0
0
0
10
0
% K
% Leu:
0
0
10
0
10
0
0
0
0
0
0
0
10
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% M
% Asn:
0
0
10
0
10
0
0
20
0
0
10
10
0
0
0
% N
% Pro:
0
0
0
10
0
0
10
0
20
0
0
0
30
10
10
% P
% Gln:
10
10
20
10
0
10
10
0
10
0
10
0
0
0
0
% Q
% Arg:
0
10
0
10
0
10
0
0
20
20
20
20
0
20
0
% R
% Ser:
10
0
20
0
0
20
0
20
0
0
10
0
10
0
30
% S
% Thr:
30
0
20
10
10
10
0
0
30
0
0
0
10
10
20
% T
% Val:
10
0
0
0
10
0
10
0
0
10
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
30
20
10
0
10
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _