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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAPLN
All Species:
12.73
Human Site:
S1166
Identified Species:
31.11
UniProt:
O95428
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95428
NP_775733.3
1278
137700
S1166
E
S
V
N
I
R
W
S
R
N
G
L
P
V
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088864
1244
134167
S1132
E
S
V
N
I
R
W
S
R
N
G
L
P
V
H
Dog
Lupus familis
XP_547891
1189
127952
I1098
S
P
D
G
T
L
L
I
H
N
L
R
A
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPX2
1280
138805
S1166
E
S
V
N
I
R
W
S
R
N
G
L
P
I
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426430
1196
131476
S1095
D
G
R
H
I
H
L
S
Q
D
G
S
L
I
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919035
930
101902
V840
G
T
L
I
L
N
N
V
Q
S
V
D
E
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q868Z9
2898
313016
S2735
R
P
V
T
Q
R
P
S
Y
P
Y
R
P
T
R
Honey Bee
Apis mellifera
XP_396472
2807
307624
F2664
I
T
I
G
Q
N
Q
F
P
E
G
S
D
V
N
Nematode Worm
Caenorhab. elegans
O76840
2167
237582
N2007
N
T
F
R
I
R
C
N
S
Y
G
V
L
P
I
Sea Urchin
Strong. purpuratus
XP_001182864
608
67786
G518
V
F
C
A
D
I
T
G
N
S
M
V
Q
V
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
91.8
72.1
N.A.
74.5
N.A.
N.A.
N.A.
51.2
N.A.
33.4
N.A.
20.3
20.9
22.5
21.7
Protein Similarity:
100
N.A.
93
78
N.A.
82.3
N.A.
N.A.
N.A.
66.1
N.A.
45.6
N.A.
28.3
29.4
32.7
31
P-Site Identity:
100
N.A.
93.3
6.6
N.A.
93.3
N.A.
N.A.
N.A.
20
N.A.
0
N.A.
26.6
13.3
20
6.6
P-Site Similarity:
100
N.A.
93.3
6.6
N.A.
100
N.A.
N.A.
N.A.
53.3
N.A.
33.3
N.A.
33.3
26.6
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
10
0
0
0
0
10
0
10
10
0
10
% D
% Glu:
30
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% E
% Phe:
0
10
10
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
20
0
0
0
10
0
0
60
0
0
20
0
% G
% His:
0
0
0
10
0
10
0
0
10
0
0
0
0
0
10
% H
% Ile:
10
0
10
10
50
10
0
10
0
0
0
0
0
20
20
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
0
10
10
20
0
0
0
10
30
20
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
10
0
0
30
0
20
10
10
10
40
0
0
0
0
10
% N
% Pro:
0
20
0
0
0
0
10
0
10
10
0
0
40
10
10
% P
% Gln:
0
0
0
0
20
0
10
0
20
0
0
0
10
0
20
% Q
% Arg:
10
0
10
10
0
50
0
0
30
0
0
20
0
0
10
% R
% Ser:
10
30
0
0
0
0
0
50
10
20
0
20
0
0
0
% S
% Thr:
0
30
0
10
10
0
10
0
0
0
0
0
0
10
10
% T
% Val:
10
0
40
0
0
0
0
10
0
0
10
20
0
40
0
% V
% Trp:
0
0
0
0
0
0
30
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
10
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _