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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IKBKAP All Species: 25.45
Human Site: Y943 Identified Species: 50.91
UniProt: O95163 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95163 NP_003631.2 1332 150254 Y943 I D K Y L K R Y E K A I G H L
Chimpanzee Pan troglodytes XP_001142839 1332 150362 Y943 I D K Y L K R Y E K A I G H L
Rhesus Macaque Macaca mulatta XP_001102913 1249 140865 N880 E Y F P E C L N L I K D K N L
Dog Lupus familis XP_855277 1355 153048 Y966 I D K Y L K R Y E K A I G H L
Cat Felis silvestris
Mouse Mus musculus Q7TT37 1333 149565 Y944 I D K Y L K R Y E K A L G H L
Rat Rattus norvegicus Q8VHU4 1331 149152 Y942 I D K Y L K R Y E K A L G H L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001231708 627 69418 K289 P F Q K G Q V K V N E L I W N
Frog Xenopus laevis Q2TAQ1 1170 132634 H832 I N A A Y G D H L V S K Q Q Y
Zebra Danio Brachydanio rerio XP_689534 1322 148531 Y933 I D K H L K R Y R K A L H H L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGK7 1252 142795 K896 E A L E Y I R K H G L Y T D G
Honey Bee Apis mellifera XP_624197 1042 121409 D704 I K A L K L F D K K S E E Y K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06706 1349 152972 Y977 I D D Y L G N Y E K A L E H L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 88 87 N.A. 80.9 80.9 N.A. N.A. 31.8 54.4 58.6 N.A. 31.8 31.9 N.A. N.A.
Protein Similarity: 100 99.4 90 92 N.A. 89 88.6 N.A. N.A. 39.1 69.1 73.4 N.A. 50.3 49.4 N.A. N.A.
P-Site Identity: 100 100 6.6 100 N.A. 93.3 93.3 N.A. N.A. 0 6.6 73.3 N.A. 6.6 13.3 N.A. N.A.
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. N.A. 20 26.6 86.6 N.A. 6.6 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 48.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 66.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 17 9 0 0 0 0 0 0 59 0 0 0 0 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 59 9 0 0 0 9 9 0 0 0 9 0 9 0 % D
% Glu: 17 0 0 9 9 0 0 0 50 0 9 9 17 0 0 % E
% Phe: 0 9 9 0 0 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 9 17 0 0 0 9 0 0 42 0 9 % G
% His: 0 0 0 9 0 0 0 9 9 0 0 0 9 59 0 % H
% Ile: 75 0 0 0 0 9 0 0 0 9 0 25 9 0 0 % I
% Lys: 0 9 50 9 9 50 0 17 9 67 9 9 9 0 9 % K
% Leu: 0 0 9 9 59 9 9 0 17 0 9 42 0 0 67 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 0 9 9 0 9 0 0 0 9 9 % N
% Pro: 9 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 9 0 0 9 0 0 0 0 0 0 9 9 0 % Q
% Arg: 0 0 0 0 0 0 59 0 9 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % T
% Val: 0 0 0 0 0 0 9 0 9 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % W
% Tyr: 0 9 0 50 17 0 0 59 0 0 0 9 0 9 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _