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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IKBKAP
All Species:
16.36
Human Site:
Y581
Identified Species:
32.73
UniProt:
O95163
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95163
NP_003631.2
1332
150254
Y581
A
D
G
Q
I
F
K
Y
L
W
E
S
P
S
L
Chimpanzee
Pan troglodytes
XP_001142839
1332
150362
Y581
A
D
G
Q
I
F
K
Y
L
W
E
S
P
S
L
Rhesus Macaque
Macaca mulatta
XP_001102913
1249
140865
K564
S
L
A
V
K
P
W
K
N
S
G
G
F
P
V
Dog
Lupus familis
XP_855277
1355
153048
Y604
A
G
G
Q
I
L
K
Y
F
W
E
S
P
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q7TT37
1333
149565
Y582
A
D
G
Q
V
L
K
Y
L
W
E
S
P
S
L
Rat
Rattus norvegicus
Q8VHU4
1331
149152
Y580
A
D
G
Q
V
L
K
Y
L
W
E
S
P
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231708
627
69418
Frog
Xenopus laevis
Q2TAQ1
1170
132634
L516
L
K
A
L
E
T
Q
L
N
S
A
S
N
P
N
Zebra Danio
Brachydanio rerio
XP_689534
1322
148531
E611
M
A
L
C
T
L
S
E
E
E
Y
F
I
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGK7
1252
142795
L572
W
D
G
Y
T
G
A
L
V
T
L
R
N
Q
H
Honey Bee
Apis mellifera
XP_624197
1042
121409
E388
K
E
A
Y
I
I
V
E
N
S
I
I
K
Y
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06706
1349
152972
D633
N
T
S
A
E
D
D
D
N
W
S
A
E
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
88
87
N.A.
80.9
80.9
N.A.
N.A.
31.8
54.4
58.6
N.A.
31.8
31.9
N.A.
N.A.
Protein Similarity:
100
99.4
90
92
N.A.
89
88.6
N.A.
N.A.
39.1
69.1
73.4
N.A.
50.3
49.4
N.A.
N.A.
P-Site Identity:
100
100
0
80
N.A.
86.6
80
N.A.
N.A.
0
6.6
6.6
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
100
13.3
80
N.A.
93.3
86.6
N.A.
N.A.
0
13.3
6.6
N.A.
20
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
9
25
9
0
0
9
0
0
0
9
9
0
0
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
42
0
0
0
9
9
9
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
17
0
0
17
9
9
42
0
9
0
0
% E
% Phe:
0
0
0
0
0
17
0
0
9
0
0
9
9
0
0
% F
% Gly:
0
9
50
0
0
9
0
0
0
0
9
9
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
34
9
0
0
0
0
9
9
9
0
0
% I
% Lys:
9
9
0
0
9
0
42
9
0
0
0
0
9
0
0
% K
% Leu:
9
9
9
9
0
34
0
17
34
0
9
0
0
0
42
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
34
0
0
0
17
0
9
% N
% Pro:
0
0
0
0
0
9
0
0
0
0
0
0
42
17
0
% P
% Gln:
0
0
0
42
0
0
9
0
0
0
0
0
0
9
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
9
0
9
0
0
0
9
0
0
25
9
50
0
50
17
% S
% Thr:
0
9
0
0
17
9
0
0
0
9
0
0
0
0
9
% T
% Val:
0
0
0
9
17
0
9
0
9
0
0
0
0
0
9
% V
% Trp:
9
0
0
0
0
0
9
0
0
50
0
0
0
0
0
% W
% Tyr:
0
0
0
17
0
0
0
42
0
0
9
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _