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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IKBKAP
All Species:
19.09
Human Site:
T1277
Identified Species:
38.18
UniProt:
O95163
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95163
NP_003631.2
1332
150254
T1277
L
P
E
I
W
T
L
T
Y
Q
Q
N
S
A
T
Chimpanzee
Pan troglodytes
XP_001142839
1332
150362
T1277
L
P
E
I
W
T
L
T
Y
Q
Q
N
S
A
T
Rhesus Macaque
Macaca mulatta
XP_001102913
1249
140865
T1194
L
P
E
I
W
T
L
T
S
Q
Q
N
S
A
T
Dog
Lupus familis
XP_855277
1355
153048
T1300
L
P
E
I
W
T
L
T
H
Q
Q
N
S
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q7TT37
1333
149565
A1278
V
P
E
I
W
T
P
A
G
Q
Q
S
S
T
T
Rat
Rattus norvegicus
Q8VHU4
1331
149152
T1276
L
P
D
I
W
T
L
T
G
Q
Q
S
S
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231708
627
69418
S576
S
Q
P
G
L
C
L
S
S
S
P
V
L
G
P
Frog
Xenopus laevis
Q2TAQ1
1170
132634
T1119
P
P
S
V
Q
Q
N
T
A
A
P
I
L
G
P
Zebra Danio
Brachydanio rerio
XP_689534
1322
148531
N1267
I
P
D
I
W
S
E
N
L
Q
P
G
Q
N
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGK7
1252
142795
E1201
L
D
E
I
W
T
P
E
L
R
G
N
G
L
M
Honey Bee
Apis mellifera
XP_624197
1042
121409
E991
E
K
I
Q
H
C
M
E
E
L
L
L
I
I
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06706
1349
152972
E1298
Q
I
Q
K
N
F
V
E
V
L
D
L
L
K
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
88
87
N.A.
80.9
80.9
N.A.
N.A.
31.8
54.4
58.6
N.A.
31.8
31.9
N.A.
N.A.
Protein Similarity:
100
99.4
90
92
N.A.
89
88.6
N.A.
N.A.
39.1
69.1
73.4
N.A.
50.3
49.4
N.A.
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
60
73.3
N.A.
N.A.
6.6
13.3
33.3
N.A.
40
0
N.A.
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
73.3
93.3
N.A.
N.A.
13.3
20
53.3
N.A.
46.6
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
9
9
0
0
0
34
9
% A
% Cys:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
17
0
0
0
0
0
0
0
9
0
0
0
0
% D
% Glu:
9
0
50
0
0
0
9
25
9
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
17
0
9
9
9
17
0
% G
% His:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
9
9
9
67
0
0
0
0
0
0
0
9
9
9
0
% I
% Lys:
0
9
0
9
0
0
0
0
0
0
0
0
0
9
0
% K
% Leu:
50
0
0
0
9
0
50
0
17
17
9
17
25
9
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
9
0
9
9
0
0
0
42
0
9
0
% N
% Pro:
9
67
9
0
0
0
17
0
0
0
25
0
0
0
17
% P
% Gln:
9
9
9
9
9
9
0
0
0
59
50
0
9
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% R
% Ser:
9
0
9
0
0
9
0
9
17
9
0
17
50
9
0
% S
% Thr:
0
0
0
0
0
59
0
50
0
0
0
0
0
9
59
% T
% Val:
9
0
0
9
0
0
9
0
9
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
67
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _