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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALX3
All Species:
26.97
Human Site:
S238
Identified Species:
65.93
UniProt:
O95076
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95076
NP_006483.2
343
36935
S238
S
V
L
P
R
T
D
S
H
P
Q
L
Q
N
S
Chimpanzee
Pan troglodytes
XP_524801
343
37015
S238
S
V
L
P
R
T
D
S
H
P
Q
L
Q
N
S
Rhesus Macaque
Macaca mulatta
XP_001099295
343
36926
S238
S
V
L
P
R
T
D
S
H
P
Q
L
Q
N
S
Dog
Lupus familis
XP_854590
446
47887
S341
S
V
L
P
R
A
A
S
H
A
Q
L
Q
N
S
Cat
Felis silvestris
Mouse
Mus musculus
O70137
343
36832
S238
S
V
L
P
R
T
D
S
H
P
Q
L
Q
N
S
Rat
Rattus norvegicus
Q63087
326
36886
S217
S
V
L
P
R
T
D
S
Y
P
Q
I
Q
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505453
802
86405
N697
D
S
Y
P
Q
L
Q
N
N
L
W
S
S
P
G
Chicken
Gallus gallus
Q9PVX0
317
34038
S213
P
V
G
A
L
G
G
S
L
P
L
E
T
W
L
Frog
Xenopus laevis
Q91574
335
37508
S226
S
V
L
P
R
A
D
S
Y
P
Q
I
Q
N
N
Zebra Danio
Brachydanio rerio
O42115
453
49378
N336
P
G
L
A
P
P
P
N
S
S
A
L
P
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
95.9
60.3
N.A.
91.8
39.6
N.A.
31.4
33.5
39.6
27.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
96.7
64.1
N.A.
94.4
51.9
N.A.
36.1
45.7
54.2
40.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
100
80
N.A.
6.6
20
73.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
100
100
N.A.
26.6
20
93.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
0
20
10
0
0
10
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
60
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
0
0
10
10
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
80
0
10
10
0
0
10
10
10
60
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
20
10
0
0
0
0
70
20
% N
% Pro:
20
0
0
80
10
10
10
0
0
70
0
0
10
20
0
% P
% Gln:
0
0
0
0
10
0
10
0
0
0
70
0
70
0
0
% Q
% Arg:
0
0
0
0
70
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
70
10
0
0
0
0
0
80
10
10
0
10
10
0
50
% S
% Thr:
0
0
0
0
0
50
0
0
0
0
0
0
10
0
0
% T
% Val:
0
80
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% W
% Tyr:
0
0
10
0
0
0
0
0
20
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _