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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNK2
All Species:
23.33
Human Site:
T378
Identified Species:
46.67
UniProt:
O95069
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95069
NP_001017424.1
426
47093
T378
G
N
H
N
Q
E
L
T
P
C
R
R
T
L
S
Chimpanzee
Pan troglodytes
XP_514195
421
46737
T373
G
N
H
N
Q
E
L
T
P
C
R
R
T
L
S
Rhesus Macaque
Macaca mulatta
XP_001083327
781
86054
L632
L
D
Q
R
A
H
S
L
D
M
L
S
P
E
K
Dog
Lupus familis
XP_849278
422
46753
T374
G
S
H
N
Q
E
L
T
P
C
R
R
T
L
S
Cat
Felis silvestris
Mouse
Mus musculus
P97438
411
45279
T363
G
N
H
N
Q
E
L
T
P
C
R
R
T
L
S
Rat
Rattus norvegicus
Q9JIS4
538
59782
L389
L
D
Q
R
A
H
S
L
D
M
L
S
P
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510388
626
67934
T578
V
N
H
N
Q
E
L
T
P
C
K
R
T
L
S
Chicken
Gallus gallus
XP_001234270
413
45532
T365
V
N
H
N
Q
D
L
T
P
C
K
R
T
L
S
Frog
Xenopus laevis
Q63ZI0
374
42700
I334
F
H
S
I
S
Y
K
I
E
E
I
S
P
S
T
Zebra Danio
Brachydanio rerio
XP_688186
490
54952
M440
Q
N
P
G
Q
D
M
M
P
C
K
R
T
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17185
329
36973
S289
L
P
L
S
D
N
V
S
L
A
S
C
S
C
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40310
691
77389
N527
S
S
Q
I
S
E
F
N
D
N
N
S
E
E
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
36.6
95.5
N.A.
92.9
49.8
N.A.
65.1
90.8
24.4
65
N.A.
N.A.
N.A.
26
N.A.
Protein Similarity:
100
97.8
44.8
97.4
N.A.
95.5
62.4
N.A.
66.7
94.3
44.1
75.3
N.A.
N.A.
N.A.
41.7
N.A.
P-Site Identity:
100
100
0
93.3
N.A.
100
0
N.A.
86.6
80
0
53.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
100
6.6
N.A.
93.3
93.3
13.3
73.3
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
17
0
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
59
0
9
0
9
0
% C
% Asp:
0
17
0
0
9
17
0
0
25
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
50
0
0
9
9
0
0
9
25
0
% E
% Phe:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
34
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
9
50
0
0
17
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
17
0
0
0
9
0
0
9
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
25
0
0
0
17
% K
% Leu:
25
0
9
0
0
0
50
17
9
0
17
0
0
59
0
% L
% Met:
0
0
0
0
0
0
9
9
0
17
0
0
0
0
0
% M
% Asn:
0
50
0
50
0
9
0
9
0
9
9
0
0
0
9
% N
% Pro:
0
9
9
0
0
0
0
0
59
0
0
0
25
0
0
% P
% Gln:
9
0
25
0
59
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
17
0
0
0
0
0
0
34
59
0
0
0
% R
% Ser:
9
17
9
9
17
0
17
9
0
0
9
34
9
9
59
% S
% Thr:
0
0
0
0
0
0
0
50
0
0
0
0
59
0
9
% T
% Val:
17
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _