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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GLCE All Species: 10.91
Human Site: T268 Identified Species: 20
UniProt: O94923 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94923 NP_056369.1 617 70101 T268 V A D K S R F T N V K Q F I A
Chimpanzee Pan troglodytes XP_510506 617 70097 T268 V A D K S R F T N V K Q F I A
Rhesus Macaque Macaca mulatta XP_001085491 618 70233 F268 N V A D K S R F T N V K Q F I
Dog Lupus familis XP_852992 616 69972 T267 V A E K S R F T N V K Q F I A
Cat Felis silvestris
Mouse Mus musculus Q9EPS3 618 70080 S268 S V A D K S R S T N V K Q F I
Rat Rattus norvegicus XP_343405 618 70100 S268 S V A D K S R S T N V K Q F I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508480 616 69238 F266 S V A D R S R F T N V K Q F V
Chicken Gallus gallus
Frog Xenopus laevis NP_001085160 607 68310 V264 N S H V K H F V V P E K S D G
Zebra Danio Brachydanio rerio NP_998014 585 66035 S251 P E N S E G V S L P L G N T K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001163062 612 69086 Q263 K F N T S V V Q F E T A P G Y
Honey Bee Apis mellifera XP_393602 542 62345 L208 T S T S G I T L K L D H V L D
Nematode Worm Caenorhab. elegans P46555 616 70037 P263 V I S F D W K P Y E A N S S F
Sea Urchin Strong. purpuratus XP_781048 661 76192 K312 P S P N G E I K I V T S D T S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.1 97.4 N.A. 95.6 95.9 N.A. 82.3 N.A. 75 73.7 N.A. 43.1 45.2 38 44.1
Protein Similarity: 100 100 99.3 98.6 N.A. 98 98.3 N.A. 91.7 N.A. 87.8 84.2 N.A. 58.3 61.9 55.2 62.1
P-Site Identity: 100 100 0 93.3 N.A. 0 0 N.A. 0 N.A. 6.6 0 N.A. 6.6 0 6.6 6.6
P-Site Similarity: 100 100 6.6 100 N.A. 13.3 13.3 N.A. 6.6 N.A. 26.6 13.3 N.A. 13.3 20 6.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 31 0 0 0 0 0 0 0 8 8 0 0 24 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 16 31 8 0 0 0 0 0 8 0 8 8 8 % D
% Glu: 0 8 8 0 8 8 0 0 0 16 8 0 0 0 0 % E
% Phe: 0 8 0 8 0 0 31 16 8 0 0 0 24 31 8 % F
% Gly: 0 0 0 0 16 8 0 0 0 0 0 8 0 8 8 % G
% His: 0 0 8 0 0 8 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 8 0 0 0 8 8 0 8 0 0 0 0 24 24 % I
% Lys: 8 0 0 24 31 0 8 8 8 0 24 39 0 0 8 % K
% Leu: 0 0 0 0 0 0 0 8 8 8 8 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 16 0 16 8 0 0 0 0 24 31 0 8 8 0 0 % N
% Pro: 16 0 8 0 0 0 0 8 0 16 0 0 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 8 0 0 0 24 31 0 0 % Q
% Arg: 0 0 0 0 8 24 31 0 0 0 0 0 0 0 0 % R
% Ser: 24 24 8 16 31 31 0 24 0 0 0 8 16 8 8 % S
% Thr: 8 0 8 8 0 0 8 24 31 0 16 0 0 16 0 % T
% Val: 31 31 0 8 0 8 16 8 8 31 31 0 8 0 8 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _