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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA8
All Species:
18.79
Human Site:
Y159
Identified Species:
41.33
UniProt:
O94911
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94911
NP_009099.1
1581
179245
Y159
K
D
H
T
A
H
C
Y
E
T
N
E
D
V
Y
Chimpanzee
Pan troglodytes
XP_001165971
1581
179231
Y159
K
D
H
T
A
H
C
Y
E
T
N
E
D
V
Y
Rhesus Macaque
Macaca mulatta
XP_001082492
1581
179168
Y159
K
D
H
T
A
H
C
Y
E
T
N
E
D
V
Y
Dog
Lupus familis
XP_548020
1622
184532
Y159
R
D
H
E
A
H
C
Y
N
L
S
E
G
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K440
1620
183021
D158
R
D
H
N
A
H
C
D
G
L
Y
E
D
V
N
Rat
Rattus norvegicus
Q8CF82
1642
185792
S160
M
D
S
R
A
G
C
S
K
S
C
D
A
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509469
1722
195635
S240
M
D
S
R
A
G
C
S
K
S
C
E
A
A
I
Chicken
Gallus gallus
XP_415691
1546
175373
V152
D
A
A
I
I
E
V
V
A
N
H
S
V
W
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001092716
1654
185619
S156
D
F
T
E
S
I
T
S
C
Y
T
N
Y
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
T187
P
E
E
T
W
H
L
T
E
T
S
Y
N
P
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
F210
M
Q
Y
S
F
S
G
F
L
T
L
Q
Q
V
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.7
77.1
N.A.
73.5
40.3
N.A.
39.4
46.1
N.A.
42.4
N.A.
N.A.
N.A.
22
N.A.
Protein Similarity:
100
99.5
97.9
85.4
N.A.
83.5
60.1
N.A.
59
63.5
N.A.
60.8
N.A.
N.A.
N.A.
41.2
N.A.
P-Site Identity:
100
100
100
53.3
N.A.
53.3
20
N.A.
26.6
0
N.A.
6.6
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
100
100
100
66.6
N.A.
60
40
N.A.
40
6.6
N.A.
13.3
N.A.
N.A.
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
64
0
0
0
10
0
0
0
19
19
0
% A
% Cys:
0
0
0
0
0
0
64
0
10
0
19
0
0
0
0
% C
% Asp:
19
64
0
0
0
0
0
10
0
0
0
10
37
0
0
% D
% Glu:
0
10
10
19
0
10
0
0
37
0
0
55
0
0
10
% E
% Phe:
0
10
0
0
10
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
19
10
0
10
0
0
0
10
0
0
% G
% His:
0
0
46
0
0
55
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
10
10
10
0
0
0
0
0
0
0
0
10
% I
% Lys:
28
0
0
0
0
0
0
0
19
0
0
0
0
0
10
% K
% Leu:
0
0
0
0
0
0
10
0
10
19
10
0
0
0
0
% L
% Met:
28
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
10
10
28
10
10
0
19
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
10
10
0
10
% Q
% Arg:
19
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
19
10
10
10
0
28
0
19
19
10
0
0
0
% S
% Thr:
0
0
10
37
0
0
10
10
0
46
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
10
0
0
0
0
10
64
10
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
10
0
0
0
0
37
0
10
10
10
10
0
37
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _