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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA8
All Species:
6.67
Human Site:
T448
Identified Species:
14.67
UniProt:
O94911
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94911
NP_009099.1
1581
179245
T448
F
W
S
Q
T
Q
K
T
D
H
V
A
L
E
D
Chimpanzee
Pan troglodytes
XP_001165971
1581
179231
T448
F
W
S
Q
T
Q
K
T
D
H
V
A
L
E
D
Rhesus Macaque
Macaca mulatta
XP_001082492
1581
179168
A448
F
W
S
Q
T
Q
K
A
D
H
V
A
L
E
D
Dog
Lupus familis
XP_548020
1622
184532
A448
F
W
S
R
Q
H
K
A
D
H
V
A
L
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8K440
1620
183021
P447
F
W
L
Q
T
R
K
P
A
H
V
I
L
E
D
Rat
Rattus norvegicus
Q8CF82
1642
185792
N446
Y
W
S
K
N
K
R
N
Y
K
E
L
S
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509469
1722
195635
N526
Y
W
S
K
N
K
R
N
Y
K
E
L
S
E
G
Chicken
Gallus gallus
XP_415691
1546
175373
T438
Y
K
K
K
D
K
K
T
E
A
L
R
G
L
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001092716
1654
185619
R446
Y
W
S
K
R
R
K
R
Y
V
E
V
S
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
R492
G
V
T
A
Q
N
T
R
I
N
E
Q
V
R
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
L504
F
G
R
K
K
N
N
L
Q
N
R
I
P
G
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.7
77.1
N.A.
73.5
40.3
N.A.
39.4
46.1
N.A.
42.4
N.A.
N.A.
N.A.
22
N.A.
Protein Similarity:
100
99.5
97.9
85.4
N.A.
83.5
60.1
N.A.
59
63.5
N.A.
60.8
N.A.
N.A.
N.A.
41.2
N.A.
P-Site Identity:
100
100
93.3
73.3
N.A.
66.6
20
N.A.
20
13.3
N.A.
20
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
93.3
80
N.A.
73.3
46.6
N.A.
46.6
46.6
N.A.
40
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
19
10
10
0
37
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
37
0
0
0
0
0
46
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
37
0
0
64
0
% E
% Phe:
55
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
10
10
0
0
0
0
0
0
0
0
0
0
10
10
19
% G
% His:
0
0
0
0
0
10
0
0
0
46
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
19
0
0
0
% I
% Lys:
0
10
10
46
10
28
64
0
0
19
0
0
0
0
0
% K
% Leu:
0
0
10
0
0
0
0
10
0
0
10
19
46
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
19
19
10
19
0
19
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% P
% Gln:
0
0
0
37
19
28
0
0
10
0
0
10
0
0
0
% Q
% Arg:
0
0
10
10
10
19
19
19
0
0
10
10
0
10
0
% R
% Ser:
0
0
64
0
0
0
0
0
0
0
0
0
28
10
10
% S
% Thr:
0
0
10
0
37
0
10
28
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
10
46
10
10
0
10
% V
% Trp:
0
73
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
37
0
0
0
0
0
0
0
28
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _