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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PROSC All Species: 53.64
Human Site: S46 Identified Species: 90.77
UniProt: O94903 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94903 NP_009129.1 275 30344 S46 Q P R L V A V S K T K P A D M
Chimpanzee Pan troglodytes XP_528110 275 30323 S46 Q P R L V A V S K T K P A D M
Rhesus Macaque Macaca mulatta XP_001089087 275 30367 S46 Q P R L V A V S K T K P A D M
Dog Lupus familis XP_539969 275 30411 S46 Q P R L V A V S K T K P V E M
Cat Felis silvestris
Mouse Mus musculus Q9Z2Y8 274 30030 S46 Q P R L V A V S K T K P A D M
Rat Rattus norvegicus NP_001100790 275 30086 S46 Q P R L V A V S K T K P T E M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513258 332 35816 S104 Q P R L V A V S K T K P A D M
Chicken Gallus gallus XP_424381 276 30053 S45 Q P R L V A V S K T K P A E M
Frog Xenopus laevis NP_001091336 261 28776 S38 D P R L V A V S K T K P V D V
Zebra Danio Brachydanio rerio NP_001119881 283 31653 S44 P P R L V A V S K T K P P E M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651776 254 28254 S44 R P L L V A V S K T K P A E A
Honey Bee Apis mellifera XP_623518 248 28280 S37 E P R L V A V S K L K P V E L
Nematode Worm Caenorhab. elegans P52057 244 27177 S36 R C R L V A V S K T K S A D L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38197 257 29105 S48 K I L L L V V S K L K P A S D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 96.7 89.8 N.A. 86.5 84 N.A. 67.7 76 66.1 65.3 N.A. 47.6 50.1 40.3 N.A.
Protein Similarity: 100 100 98.9 95.6 N.A. 90.9 90.9 N.A. 74.4 87.6 81 79.1 N.A. 68 65.8 56.3 N.A.
P-Site Identity: 100 100 100 86.6 N.A. 100 86.6 N.A. 100 93.3 80 80 N.A. 73.3 66.6 73.3 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 93.3 N.A. 100 100 86.6 86.6 N.A. 86.6 86.6 86.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 37 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 54.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 93 0 0 0 0 0 0 65 0 8 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 0 0 0 0 50 8 % D
% Glu: 8 0 0 0 0 0 0 0 0 0 0 0 0 43 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 0 0 0 0 0 0 100 0 100 0 0 0 0 % K
% Leu: 0 0 15 100 8 0 0 0 0 15 0 0 0 0 15 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 65 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 86 0 0 0 0 0 0 0 0 0 93 8 0 0 % P
% Gln: 58 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 15 0 86 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 100 0 0 0 8 0 8 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 86 0 0 8 0 0 % T
% Val: 0 0 0 0 93 8 100 0 0 0 0 0 22 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _