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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PROSC
All Species:
37.27
Human Site:
S222
Identified Species:
63.08
UniProt:
O94903
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94903
NP_009129.1
275
30344
S222
P
A
D
Q
V
E
L
S
M
G
M
S
A
D
F
Chimpanzee
Pan troglodytes
XP_528110
275
30323
S222
P
A
D
Q
V
E
L
S
M
G
M
S
A
D
F
Rhesus Macaque
Macaca mulatta
XP_001089087
275
30367
S222
P
A
D
Q
V
E
L
S
M
G
M
S
V
D
F
Dog
Lupus familis
XP_539969
275
30411
S222
P
P
E
Q
V
E
L
S
M
G
M
S
M
D
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2Y8
274
30030
S222
P
V
E
Q
V
E
L
S
M
G
M
S
M
D
F
Rat
Rattus norvegicus
NP_001100790
275
30086
S222
P
V
E
Q
V
E
L
S
M
G
M
S
V
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513258
332
35816
S280
S
T
D
S
V
E
L
S
M
G
M
S
M
D
F
Chicken
Gallus gallus
XP_424381
276
30053
S221
P
I
E
K
V
E
L
S
M
G
M
S
T
D
F
Frog
Xenopus laevis
NP_001091336
261
28776
S214
Q
I
D
S
V
E
L
S
M
G
M
S
S
D
F
Zebra Danio
Brachydanio rerio
NP_001119881
283
31653
S222
P
L
E
Q
V
E
L
S
M
G
M
S
T
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651776
254
28254
H212
H
R
S
I
C
E
A
H
S
L
A
P
D
S
V
Honey Bee
Apis mellifera
XP_623518
248
28280
K203
E
C
R
E
N
V
S
K
Q
L
D
I
D
L
K
Nematode Worm
Caenorhab. elegans
P52057
244
27177
T201
R
Q
T
W
A
E
Q
T
G
E
S
A
D
S
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38197
257
29105
T215
K
I
D
A
K
F
G
T
S
L
K
L
S
M
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.7
89.8
N.A.
86.5
84
N.A.
67.7
76
66.1
65.3
N.A.
47.6
50.1
40.3
N.A.
Protein Similarity:
100
100
98.9
95.6
N.A.
90.9
90.9
N.A.
74.4
87.6
81
79.1
N.A.
68
65.8
56.3
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
80
80
N.A.
73.3
73.3
73.3
80
N.A.
6.6
0
6.6
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
86.6
86.6
N.A.
73.3
86.6
80
86.6
N.A.
6.6
6.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
22
0
8
8
0
8
0
0
0
8
8
15
0
0
% A
% Cys:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
43
0
0
0
0
0
0
0
8
0
22
72
0
% D
% Glu:
8
0
36
8
0
86
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
72
% F
% Gly:
0
0
0
0
0
0
8
0
8
72
0
0
0
0
8
% G
% His:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
22
0
8
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
8
0
0
8
8
0
0
8
0
0
8
0
0
0
8
% K
% Leu:
0
8
0
0
0
0
72
0
0
22
0
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
72
0
72
0
22
8
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
58
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
8
8
0
50
0
0
8
0
8
0
0
0
0
0
0
% Q
% Arg:
8
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
8
15
0
0
8
72
15
0
8
72
15
15
0
% S
% Thr:
0
8
8
0
0
0
0
15
0
0
0
0
15
0
0
% T
% Val:
0
15
0
0
72
8
0
0
0
0
0
0
15
0
15
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _