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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24D All Species: 10.61
Human Site: S857 Identified Species: 17.95
UniProt: O94855 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94855 NP_055637.2 1032 113010 S857 L K N C V L L S R P E I S T D
Chimpanzee Pan troglodytes XP_001145058 1094 118246 P919 L K S D V L Q P G A E V T T D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535702 1171 127156 S996 L K N C V L L S R P E I S T D
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 T911 L K Q K S F Q T G T S I R L D
Rat Rattus norvegicus NP_001102926 1095 118506 P920 L K S D V L Q P G A E V T T D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513076 1029 112278 S854 L K N C V L L S R P E I S T D
Chicken Gallus gallus XP_420635 1038 113834 G863 L K S S V L T G R P E I P T D
Frog Xenopus laevis NP_001087832 1126 123503 P951 L K S D V L Q P G T E M T T D
Zebra Danio Brachydanio rerio XP_700597 1315 142554 P1142 L K S D V L Q P G A D V S L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392952 1276 140829 G1100 L K S D A L S G G A D M S I D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783728 1150 123558 G975 L K S D A F S G T T D I T T D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M291 1097 117779 M922 T K G V G L R M D G R I D D R
Baker's Yeast Sacchar. cerevisiae P40482 926 103617 D774 G L P V Q T E D G E A T G T I
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 L794 M Q Y I Y P R L Y S L H D M P
Conservation
Percent
Protein Identity: 100 55.6 N.A. 81 N.A. 26.9 55.4 N.A. 76.1 75.3 54.3 49.9 N.A. N.A. 41.3 N.A. 47.6
Protein Similarity: 100 70.8 N.A. 83.5 N.A. 44.4 70.5 N.A. 85.3 84.9 69.3 61.6 N.A. N.A. 56.8 N.A. 63.1
P-Site Identity: 100 46.6 N.A. 100 N.A. 26.6 46.6 N.A. 100 66.6 46.6 40 N.A. N.A. 33.3 N.A. 33.3
P-Site Similarity: 100 66.6 N.A. 100 N.A. 33.3 66.6 N.A. 100 73.3 66.6 60 N.A. N.A. 53.3 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. 32.4 27.2 28
Protein Similarity: N.A. N.A. N.A. 50.5 44.3 47.2
P-Site Identity: N.A. N.A. N.A. 20 6.6 0
P-Site Similarity: N.A. N.A. N.A. 20 6.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 15 0 0 0 0 29 8 0 0 0 0 % A
% Cys: 0 0 0 22 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 43 0 0 0 8 8 0 22 0 15 8 79 % D
% Glu: 0 0 0 0 0 0 8 0 0 8 50 0 0 0 0 % E
% Phe: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 8 0 8 0 0 22 50 8 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 0 0 50 0 8 8 % I
% Lys: 0 86 0 8 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 79 8 0 0 0 72 22 8 0 0 8 0 0 15 0 % L
% Met: 8 0 0 0 0 0 0 8 0 0 0 15 0 8 0 % M
% Asn: 0 0 22 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 8 0 0 8 0 29 0 29 0 0 8 0 8 % P
% Gln: 0 8 8 0 8 0 36 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 15 0 29 0 8 0 8 0 8 % R
% Ser: 0 0 50 8 8 0 15 22 0 8 8 0 36 0 0 % S
% Thr: 8 0 0 0 0 8 8 8 8 22 0 8 29 65 0 % T
% Val: 0 0 0 15 58 0 0 0 0 0 0 22 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 8 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _