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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TOMM70A All Species: 37.88
Human Site: S253 Identified Species: 59.52
UniProt: O94826 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94826 NP_055635.3 608 67455 S253 N R E P L M P S P Q F I K S Y
Chimpanzee Pan troglodytes XP_526255 608 67420 S253 N R E P L M P S P Q F I K S Y
Rhesus Macaque Macaca mulatta XP_001092332 608 67411 S253 N R E P L M P S P Q F I K S Y
Dog Lupus familis XP_535719 806 89023 S451 N R E P L M P S P Q F I K S Y
Cat Felis silvestris
Mouse Mus musculus Q9CZW5 611 67503 S256 N R E P L M P S P Q F I K S Y
Rat Rattus norvegicus Q75Q39 610 67426 S255 N R E P L M P S P Q F I K S Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518993 530 60157 K224 N S G Y L K A K Q Y M E E E N
Chicken Gallus gallus XP_416605 583 65057 S228 N R E P L M P S P Q F I K S Y
Frog Xenopus laevis NP_001083124 576 64700 Q223 E P L M P S P Q F I K S Y F S
Zebra Danio Brachydanio rerio NP_956296 578 65091 S223 N R E P L M P S P Q F I K S Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609536 589 66345 P225 K G M R N R V P V V P S A C F
Honey Bee Apis mellifera XP_001121853 544 61521 G224 A N K K L V M G F A K A L K C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001182761 571 62840 S223 E R V P S L P S G Q F I Q S Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P07213 617 70105 S253 D K Q E N L P S V T S M A S F
Red Bread Mold Neurospora crassa P23231 624 69413 P265 E I L E T K P P K L P S S T F
Conservation
Percent
Protein Identity: 100 99.8 99.3 73.3 N.A. 92.8 92.9 N.A. 80.5 87 81.2 80.2 N.A. 37.9 39.1 N.A. 50.8
Protein Similarity: 100 100 99.6 74.5 N.A. 96.5 96.5 N.A. 83.5 91.7 88.1 87 N.A. 58.2 57.7 N.A. 65.7
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 13.3 100 6.6 100 N.A. 0 6.6 N.A. 60
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 20 100 6.6 100 N.A. 6.6 20 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.4 27
Protein Similarity: N.A. N.A. N.A. N.A. 44 45.5
P-Site Identity: N.A. N.A. N.A. N.A. 20 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 60 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 0 7 0 0 7 0 7 14 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 7 % C
% Asp: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 20 0 54 14 0 0 0 0 0 0 0 7 7 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 14 0 60 0 0 7 20 % F
% Gly: 0 7 7 0 0 0 0 7 7 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 0 7 0 60 0 0 0 % I
% Lys: 7 7 7 7 0 14 0 7 7 0 14 0 54 7 0 % K
% Leu: 0 0 14 0 67 14 0 0 0 7 0 0 7 0 0 % L
% Met: 0 0 7 7 0 54 7 0 0 0 7 7 0 0 0 % M
% Asn: 60 7 0 0 14 0 0 0 0 0 0 0 0 0 7 % N
% Pro: 0 7 0 60 7 0 80 14 54 0 14 0 0 0 0 % P
% Gln: 0 0 7 0 0 0 0 7 7 60 0 0 7 0 0 % Q
% Arg: 0 60 0 7 0 7 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 7 0 0 7 7 0 67 0 0 7 20 7 67 7 % S
% Thr: 0 0 0 0 7 0 0 0 0 7 0 0 0 7 0 % T
% Val: 0 0 7 0 0 7 7 0 14 7 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 7 0 0 7 0 60 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _