Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRKD3 All Species: 22.42
Human Site: S254 Identified Species: 61.67
UniProt: O94806 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94806 NP_005804.1 890 100471 S254 S K R I P S W S G R P I W M E
Chimpanzee Pan troglodytes XP_515412 914 103213 S254 S K R I P S W S G R P I W M E
Rhesus Macaque Macaca mulatta XP_001108366 890 100428 S254 S K R I P S W S G R P I W M E
Dog Lupus familis XP_540151 890 100382 S254 S K R I P S W S G R P I W M E
Cat Felis silvestris
Mouse Mus musculus Q8K1Y2 889 100060 S254 S K R I P S W S G R P I W M E
Rat Rattus norvegicus Q9WTQ1 918 102025 V259 R S N S Q S Y V G R P I Q L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509033 744 83197 R180 E M L W G L V R Q G L K C E G
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_685483 891 100383 S252 G K R I P S W S G R P I W M E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O45818 1070 120565 A421 P S S T L G G A A T P N I F I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.3 99.5 97.1 N.A. 95.7 68.4 N.A. 76.4 N.A. N.A. 82 N.A. N.A. N.A. 45.1 N.A.
Protein Similarity: 100 97.3 99.6 98.7 N.A. 97.8 79 N.A. 79.7 N.A. N.A. 89.4 N.A. N.A. N.A. 57.8 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 33.3 N.A. 0 N.A. N.A. 93.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 53.3 N.A. 0 N.A. N.A. 93.3 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 12 12 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % D
% Glu: 12 0 0 0 0 0 0 0 0 0 0 0 0 12 67 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % F
% Gly: 12 0 0 0 12 12 12 0 78 12 0 0 0 0 12 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 67 0 0 0 0 0 0 0 78 12 0 12 % I
% Lys: 0 67 0 0 0 0 0 0 0 0 0 12 0 0 0 % K
% Leu: 0 0 12 0 12 12 0 0 0 0 12 0 0 12 0 % L
% Met: 0 12 0 0 0 0 0 0 0 0 0 0 0 67 0 % M
% Asn: 0 0 12 0 0 0 0 0 0 0 0 12 0 0 0 % N
% Pro: 12 0 0 0 67 0 0 0 0 0 89 0 0 0 0 % P
% Gln: 0 0 0 0 12 0 0 0 12 0 0 0 12 0 0 % Q
% Arg: 12 0 67 0 0 0 0 12 0 78 0 0 0 0 0 % R
% Ser: 56 23 12 12 0 78 0 67 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 12 0 0 0 0 0 12 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 12 12 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 12 0 0 67 0 0 0 0 0 67 0 0 % W
% Tyr: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _