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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTL6B
All Species:
20.61
Human Site:
Y290
Identified Species:
34.87
UniProt:
O94805
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94805
NP_057272.1
426
46877
Y290
H
Y
E
M
P
N
G
Y
N
T
D
Y
G
A
E
Chimpanzee
Pan troglodytes
XP_001140943
374
41374
A244
G
Y
N
T
D
Y
G
A
E
R
L
R
I
P
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850533
409
44735
M279
D
E
Q
V
A
A
Q
M
P
T
V
H
Y
E
M
Cat
Felis silvestris
Mouse
Mus musculus
Q99MR0
426
46873
Y290
H
Y
E
M
P
N
G
Y
N
T
D
Y
G
A
E
Rat
Rattus norvegicus
NP_001034122
429
47402
Y293
H
Y
E
F
P
N
G
Y
N
C
D
F
G
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521333
303
33827
G172
N
G
Y
N
C
D
F
G
A
E
R
L
K
I
P
Chicken
Gallus gallus
XP_422784
720
79965
Y584
H
Y
E
F
P
N
G
Y
N
C
D
F
G
A
E
Frog
Xenopus laevis
NP_001080451
429
47605
Y293
H
Y
E
F
P
N
G
Y
N
C
D
F
G
A
E
Zebra Danio
Brachydanio rerio
NP_775347
429
47223
Y293
H
Y
E
L
P
N
G
Y
N
C
D
F
G
A
E
Tiger Blowfish
Takifugu rubipres
P53480
377
41956
G247
K
S
Y
E
L
P
D
G
Q
V
I
T
I
G
N
Fruit Fly
Dros. melanogaster
NP_611209
425
47301
T289
R
V
A
A
Q
I
P
T
V
H
Y
E
F
P
N
Honey Bee
Apis mellifera
XP_625202
440
49061
D304
F
P
T
G
Y
H
Q
D
F
G
S
E
R
F
R
Nematode Worm
Caenorhab. elegans
P10986
376
41759
G246
K
S
Y
E
L
P
D
G
Q
V
I
T
V
G
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M92
441
48918
R305
T
L
E
I
G
A
D
R
F
K
V
P
D
V
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.7
N.A.
93.9
N.A.
99.7
84.1
N.A.
64
52.2
83.6
83.6
36.3
57.2
60.6
36.8
N.A.
Protein Similarity:
100
87.7
N.A.
95
N.A.
100
92.5
N.A.
68.3
56.2
91.8
92.3
54.2
75.1
77.2
54.2
N.A.
P-Site Identity:
100
20
N.A.
6.6
N.A.
100
80
N.A.
0
80
80
80
0
0
0
0
N.A.
P-Site Similarity:
100
20
N.A.
26.6
N.A.
100
86.6
N.A.
13.3
86.6
86.6
93.3
0
0
6.6
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
15
0
8
8
0
0
0
0
43
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
29
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
8
22
8
0
0
43
0
8
0
0
% D
% Glu:
0
8
50
15
0
0
0
0
8
8
0
15
0
8
50
% E
% Phe:
8
0
0
22
0
0
8
0
15
0
0
29
8
8
0
% F
% Gly:
8
8
0
8
8
0
50
22
0
8
0
0
43
15
0
% G
% His:
43
0
0
0
0
8
0
0
0
8
0
8
0
0
0
% H
% Ile:
0
0
0
8
0
8
0
0
0
0
15
0
15
8
0
% I
% Lys:
15
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% K
% Leu:
0
8
0
8
15
0
0
0
0
0
8
8
0
0
0
% L
% Met:
0
0
0
15
0
0
0
8
0
0
0
0
0
0
15
% M
% Asn:
8
0
8
8
0
43
0
0
43
0
0
0
0
0
22
% N
% Pro:
0
8
0
0
43
15
8
0
8
0
0
8
0
15
8
% P
% Gln:
0
0
8
0
8
0
15
0
15
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
8
0
8
8
8
8
0
8
% R
% Ser:
0
15
0
0
0
0
0
0
0
0
8
0
0
0
0
% S
% Thr:
8
0
8
8
0
0
0
8
0
22
0
15
0
0
0
% T
% Val:
0
8
0
8
0
0
0
0
8
15
15
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
50
22
0
8
8
0
43
0
0
8
15
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _