KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTL6B
All Species:
33.94
Human Site:
Y27
Identified Species:
57.44
UniProt:
O94805
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94805
NP_057272.1
426
46877
Y27
S
F
S
V
R
A
G
Y
A
G
E
D
C
P
K
Chimpanzee
Pan troglodytes
XP_001140943
374
41374
L14
G
G
D
E
V
G
A
L
V
F
D
I
G
S
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850533
409
44735
Y27
S
F
S
V
R
A
G
Y
A
G
E
D
C
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q99MR0
426
46873
Y27
S
F
S
V
R
A
G
Y
A
G
E
D
C
P
K
Rat
Rattus norvegicus
NP_001034122
429
47402
Y27
S
Y
T
V
R
A
G
Y
A
G
E
D
C
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521333
303
33827
Chicken
Gallus gallus
XP_422784
720
79965
Y27
S
Y
T
V
R
A
G
Y
A
G
E
D
C
P
K
Frog
Xenopus laevis
NP_001080451
429
47605
Y27
S
Y
S
V
R
A
G
Y
A
G
E
D
C
P
K
Zebra Danio
Brachydanio rerio
NP_775347
429
47223
Y27
S
Y
S
V
R
A
G
Y
A
G
E
D
C
A
K
Tiger Blowfish
Takifugu rubipres
P53480
377
41956
G17
L
V
C
D
N
G
S
G
L
V
K
A
G
F
A
Fruit Fly
Dros. melanogaster
NP_611209
425
47301
Y29
H
H
S
L
R
V
G
Y
A
Q
E
D
S
P
K
Honey Bee
Apis mellifera
XP_625202
440
49061
Y28
H
H
S
L
R
V
G
Y
A
Q
E
D
T
P
K
Nematode Worm
Caenorhab. elegans
P10986
376
41759
S15
A
L
V
V
D
N
G
S
G
M
C
K
A
G
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M92
441
48918
E44
I
G
A
V
D
G
V
E
A
M
D
V
D
V
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.7
N.A.
93.9
N.A.
99.7
84.1
N.A.
64
52.2
83.6
83.6
36.3
57.2
60.6
36.8
N.A.
Protein Similarity:
100
87.7
N.A.
95
N.A.
100
92.5
N.A.
68.3
56.2
91.8
92.3
54.2
75.1
77.2
54.2
N.A.
P-Site Identity:
100
0
N.A.
100
N.A.
100
86.6
N.A.
0
86.6
93.3
86.6
0
60
60
13.3
N.A.
P-Site Similarity:
100
6.6
N.A.
100
N.A.
100
100
N.A.
0
100
100
93.3
6.6
66.6
66.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
50
8
0
72
0
0
8
8
8
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
8
0
50
0
0
% C
% Asp:
0
0
8
8
15
0
0
0
0
0
15
65
8
0
8
% D
% Glu:
0
0
0
8
0
0
0
8
0
0
65
0
0
0
0
% E
% Phe:
0
22
0
0
0
0
0
0
0
8
0
0
0
8
15
% F
% Gly:
8
15
0
0
0
22
72
8
8
50
0
0
15
8
0
% G
% His:
15
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
65
% K
% Leu:
8
8
0
15
0
0
0
8
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
58
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% Q
% Arg:
0
0
0
0
65
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
50
0
50
0
0
0
8
8
0
0
0
0
8
8
0
% S
% Thr:
0
0
15
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
8
8
65
8
15
8
0
8
8
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
29
0
0
0
0
0
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _