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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTL6B
All Species:
24.85
Human Site:
S244
Identified Species:
42.05
UniProt:
O94805
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94805
NP_057272.1
426
46877
S244
K
E
K
L
P
Q
V
S
K
S
W
H
N
Y
M
Chimpanzee
Pan troglodytes
XP_001140943
374
41374
Y198
V
S
K
S
W
H
N
Y
M
C
N
E
V
I
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850533
409
44735
N233
V
R
E
G
A
P
P
N
W
K
K
K
E
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99MR0
426
46873
S244
K
E
K
L
P
Q
V
S
K
S
W
H
N
Y
M
Rat
Rattus norvegicus
NP_001034122
429
47402
T247
K
E
K
L
P
Q
V
T
R
S
W
H
N
Y
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521333
303
33827
N126
Q
V
T
R
S
W
H
N
Y
M
C
N
C
V
I
Chicken
Gallus gallus
XP_422784
720
79965
T247
K
E
K
L
P
Q
V
T
R
S
W
H
N
Y
M
Frog
Xenopus laevis
NP_001080451
429
47605
T247
K
E
K
L
P
Q
V
T
R
S
W
H
N
Y
M
Zebra Danio
Brachydanio rerio
NP_775347
429
47223
T247
K
E
K
L
P
Q
V
T
R
S
W
H
N
Y
M
Tiger Blowfish
Takifugu rubipres
P53480
377
41956
S201
I
L
T
E
R
G
Y
S
F
V
T
T
A
E
R
Fruit Fly
Dros. melanogaster
NP_611209
425
47301
T243
E
R
D
N
G
R
F
T
L
R
K
L
P
E
N
Honey Bee
Apis mellifera
XP_625202
440
49061
W258
L
P
E
V
T
K
S
W
H
N
Y
M
V
K
K
Nematode Worm
Caenorhab. elegans
P10986
376
41759
S200
I
L
T
E
R
G
Y
S
F
T
T
T
A
E
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M92
441
48918
Q259
E
S
Y
K
L
F
C
Q
R
M
I
V
G
D
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.7
N.A.
93.9
N.A.
99.7
84.1
N.A.
64
52.2
83.6
83.6
36.3
57.2
60.6
36.8
N.A.
Protein Similarity:
100
87.7
N.A.
95
N.A.
100
92.5
N.A.
68.3
56.2
91.8
92.3
54.2
75.1
77.2
54.2
N.A.
P-Site Identity:
100
6.6
N.A.
0
N.A.
100
86.6
N.A.
0
86.6
86.6
86.6
6.6
0
0
6.6
N.A.
P-Site Similarity:
100
6.6
N.A.
20
N.A.
100
100
N.A.
26.6
100
100
100
6.6
20
33.3
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
0
0
15
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
8
8
0
8
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
15
43
15
15
0
0
0
0
0
0
0
8
8
22
0
% E
% Phe:
0
0
0
0
0
8
8
0
15
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
8
15
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
8
8
0
8
0
0
43
0
0
0
% H
% Ile:
15
0
0
0
0
0
0
0
0
0
8
0
0
8
15
% I
% Lys:
43
0
50
8
0
8
0
0
15
8
15
8
0
15
8
% K
% Leu:
8
15
0
43
8
0
0
0
8
0
0
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
8
15
0
8
0
0
43
% M
% Asn:
0
0
0
8
0
0
8
15
0
8
8
8
43
0
8
% N
% Pro:
0
8
0
0
43
8
8
0
0
0
0
0
8
0
0
% P
% Gln:
8
0
0
0
0
43
0
8
0
0
0
0
0
0
8
% Q
% Arg:
0
15
0
8
15
8
0
0
36
8
0
0
0
0
15
% R
% Ser:
0
15
0
8
8
0
8
29
0
43
0
0
0
0
0
% S
% Thr:
0
0
22
0
8
0
0
36
0
8
15
15
0
0
0
% T
% Val:
15
8
0
8
0
0
43
0
0
8
0
8
15
8
0
% V
% Trp:
0
0
0
0
8
8
0
8
8
0
43
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
15
8
8
0
8
0
0
43
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _