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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RECQL5
All Species:
15.45
Human Site:
S538
Identified Species:
34
UniProt:
O94762
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94762
NP_001003715.1
991
108858
S538
N
C
P
L
K
E
A
S
S
R
R
I
P
R
L
Chimpanzee
Pan troglodytes
XP_001144082
991
108864
S538
N
C
P
L
K
E
A
S
S
R
R
I
P
R
L
Rhesus Macaque
Macaca mulatta
XP_001098095
991
108681
C538
N
C
P
L
K
E
A
C
S
R
R
I
P
R
L
Dog
Lupus familis
XP_540436
989
108541
S535
D
C
P
L
K
E
A
S
S
R
K
I
P
R
L
Cat
Felis silvestris
Mouse
Mus musculus
NP_569721
982
108227
S539
D
C
P
L
R
E
A
S
S
R
K
I
P
K
L
Rat
Rattus norvegicus
NP_001099323
973
107203
E524
K
G
K
E
A
K
P
E
E
F
T
P
P
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519897
509
55570
A74
I
V
V
S
P
L
I
A
L
I
Q
D
Q
V
D
Chicken
Gallus gallus
XP_001233565
1018
112529
F514
D
C
P
L
K
D
A
F
S
R
R
I
S
K
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694922
936
104014
S501
D
L
F
K
K
Q
M
S
L
R
K
G
S
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_729983
1058
121182
A522
N
L
R
K
Q
I
S
A
A
R
Q
L
E
Q
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795300
1122
123964
D648
Q
E
P
L
K
G
R
D
N
S
K
Q
T
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
95.9
83.4
N.A.
78.8
76.8
N.A.
39.4
57.5
N.A.
47.9
N.A.
34
N.A.
N.A.
35.2
Protein Similarity:
100
99.2
97.2
88.5
N.A.
85.8
84.4
N.A.
44.4
71.2
N.A.
62.7
N.A.
48.7
N.A.
N.A.
49.9
P-Site Identity:
100
100
93.3
86.6
N.A.
73.3
6.6
N.A.
0
66.6
N.A.
20
N.A.
13.3
N.A.
N.A.
26.6
P-Site Similarity:
100
100
93.3
100
N.A.
100
13.3
N.A.
13.3
86.6
N.A.
40
N.A.
60
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
55
19
10
0
0
0
0
0
10
% A
% Cys:
0
55
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
37
0
0
0
0
10
0
10
0
0
0
10
0
10
10
% D
% Glu:
0
10
0
10
0
46
0
10
10
0
0
0
10
0
19
% E
% Phe:
0
0
10
0
0
0
0
10
0
10
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
10
0
0
0
0
0
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
10
10
0
0
10
0
55
0
0
0
% I
% Lys:
10
0
10
19
64
10
0
0
0
0
37
0
0
19
0
% K
% Leu:
0
19
0
64
0
10
0
0
19
0
0
10
0
0
64
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
37
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
64
0
10
0
10
0
0
0
0
10
55
0
0
% P
% Gln:
10
0
0
0
10
10
0
0
0
0
19
10
10
10
0
% Q
% Arg:
0
0
10
0
10
0
10
0
0
73
37
0
0
37
0
% R
% Ser:
0
0
0
10
0
0
10
46
55
10
0
0
19
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
0
10
10
0
% T
% Val:
0
10
10
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _