KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RECQL4
All Species:
8.18
Human Site:
Y353
Identified Species:
22.5
UniProt:
O94761
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94761
NP_004251.2
1208
133077
Y353
A
R
H
D
R
G
N
Y
V
R
L
N
M
K
Q
Chimpanzee
Pan troglodytes
XP_520023
1208
133141
Y353
A
R
H
D
R
G
N
Y
I
R
L
N
M
K
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539222
1209
131690
H350
K
W
R
K
K
G
E
H
F
G
G
S
Q
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q75NR7
1216
135105
Y345
A
S
L
D
R
G
N
Y
I
R
L
N
M
K
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9I920
1142
126164
A342
L
A
A
A
A
G
S
A
P
G
P
H
P
T
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920631
1380
154059
F480
T
K
N
T
D
G
N
F
V
K
I
N
L
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393782
1284
145763
F387
E
G
K
T
N
E
N
F
V
R
I
N
L
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001187631
1990
223246
R810
S
P
K
K
G
K
R
R
R
S
Y
R
R
K
G
Poplar Tree
Populus trichocarpa
XP_002315627
901
101082
D204
V
E
M
E
S
V
C
D
E
E
G
L
V
T
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
N.A.
57.8
N.A.
65.9
N.A.
N.A.
N.A.
21.1
N.A.
41.2
N.A.
N.A.
33.2
N.A.
27
Protein Similarity:
100
99.2
N.A.
66.7
N.A.
75
N.A.
N.A.
N.A.
35.4
N.A.
56.5
N.A.
N.A.
51.3
N.A.
39.3
P-Site Identity:
100
86.6
N.A.
6.6
N.A.
73.3
N.A.
N.A.
N.A.
6.6
N.A.
33.3
N.A.
N.A.
33.3
N.A.
6.6
P-Site Similarity:
100
100
N.A.
33.3
N.A.
80
N.A.
N.A.
N.A.
20
N.A.
80
N.A.
N.A.
60
N.A.
13.3
Percent
Protein Identity:
25
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
42
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
12
12
12
12
0
0
12
0
0
0
0
0
12
12
% A
% Cys:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
34
12
0
0
12
0
0
0
0
0
0
0
% D
% Glu:
12
12
0
12
0
12
12
0
12
12
0
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
23
12
0
0
0
0
0
0
% F
% Gly:
0
12
0
0
12
67
0
0
0
23
23
0
0
0
12
% G
% His:
0
0
23
0
0
0
0
12
0
0
0
12
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
23
0
23
0
0
0
0
% I
% Lys:
12
12
23
23
12
12
0
0
0
12
0
0
0
67
23
% K
% Leu:
12
0
12
0
0
0
0
0
0
0
34
12
23
0
0
% L
% Met:
0
0
12
0
0
0
0
0
0
0
0
0
34
0
0
% M
% Asn:
0
0
12
0
12
0
56
0
0
0
0
56
0
0
12
% N
% Pro:
0
12
0
0
0
0
0
0
12
0
12
0
12
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
12
% Q
% Arg:
0
23
12
0
34
0
12
12
12
45
0
12
12
0
23
% R
% Ser:
12
12
0
0
12
0
12
0
0
12
0
12
0
0
0
% S
% Thr:
12
0
0
23
0
0
0
0
0
0
0
0
0
23
0
% T
% Val:
12
0
0
0
0
12
0
0
34
0
0
0
12
0
0
% V
% Trp:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _