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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOM3Z
All Species:
17.58
Human Site:
Y186
Identified Species:
35.15
UniProt:
O77932
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O77932
NP_005501.2
396
44929
Y186
P
L
L
R
E
L
M
Y
M
G
Y
K
F
E
Q
Chimpanzee
Pan troglodytes
XP_001161885
396
44867
Y186
P
L
L
R
E
L
M
Y
M
G
Y
K
F
E
Q
Rhesus Macaque
Macaca mulatta
XP_001106541
251
28178
E47
M
Y
M
G
Y
K
F
E
Q
Y
M
C
A
D
K
Dog
Lupus familis
XP_538842
347
39553
Q143
Y
M
G
Y
K
F
E
Q
Y
M
C
A
D
K
P
Cat
Felis silvestris
Mouse
Mus musculus
O70348
397
45262
Y186
P
L
L
R
E
L
M
Y
M
G
Y
K
F
E
Q
Rat
Rattus norvegicus
Q6MG77
397
45281
Y186
P
L
L
R
E
L
M
Y
M
G
Y
K
F
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512198
126
14180
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5HZT0
401
46175
E194
A
A
Q
K
K
R
K
E
R
S
L
E
Q
E
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10660
393
45840
I173
A
I
K
R
K
G
V
I
F
L
C
E
E
K
T
Sea Urchin
Strong. purpuratus
XP_783738
649
73632
Y200
D
R
E
Q
E
M
S
Y
W
G
Y
K
F
E
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RY73
544
60363
M316
N
R
H
E
P
W
E
M
G
V
H
K
R
N
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9HE87
383
44364
T168
Y
W
G
Y
K
F
E
T
L
S
T
L
P
K
P
Conservation
Percent
Protein Identity:
100
99.2
60.6
77.5
N.A.
90.1
90.4
N.A.
23.4
N.A.
52.6
N.A.
N.A.
N.A.
N.A.
25.5
28.8
Protein Similarity:
100
99.4
62.3
81.3
N.A.
93.9
94.2
N.A.
29
N.A.
65.5
N.A.
N.A.
N.A.
N.A.
45.9
41.6
P-Site Identity:
100
100
0
0
N.A.
100
100
N.A.
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
53.3
P-Site Similarity:
100
100
20
20
N.A.
100
100
N.A.
0
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
40
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
N.A.
29.2
Protein Similarity:
N.A.
N.A.
N.A.
36.7
N.A.
43.4
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
0
0
0
0
0
0
0
0
0
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
17
9
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% D
% Glu:
0
0
9
9
42
0
25
17
0
0
0
17
9
50
0
% E
% Phe:
0
0
0
0
0
17
9
0
9
0
0
0
42
0
0
% F
% Gly:
0
0
17
9
0
9
0
0
9
42
0
0
0
0
9
% G
% His:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
9
34
9
9
0
0
0
0
50
0
25
9
% K
% Leu:
0
34
34
0
0
34
0
0
9
9
9
9
0
0
0
% L
% Met:
9
9
9
0
0
9
34
9
34
9
9
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
34
0
0
0
9
0
0
0
0
0
0
0
9
0
17
% P
% Gln:
0
0
9
9
0
0
0
9
9
0
0
0
9
0
42
% Q
% Arg:
0
17
0
42
0
9
0
0
9
0
0
0
9
0
9
% R
% Ser:
0
0
0
0
0
0
9
0
0
17
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
9
% T
% Val:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% V
% Trp:
0
9
0
0
0
9
0
0
9
0
0
0
0
0
0
% W
% Tyr:
17
9
0
17
9
0
0
42
9
9
42
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _