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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOM3Z
All Species:
13.94
Human Site:
T249
Identified Species:
27.88
UniProt:
O77932
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O77932
NP_005501.2
396
44929
T249
A
P
S
T
Q
P
P
T
C
Y
V
E
L
K
T
Chimpanzee
Pan troglodytes
XP_001161885
396
44867
T249
A
P
S
T
Q
P
P
T
C
Y
V
E
L
K
T
Rhesus Macaque
Macaca mulatta
XP_001106541
251
28178
K110
P
T
C
Y
V
E
L
K
T
S
K
E
M
H
S
Dog
Lupus familis
XP_538842
347
39553
T206
T
C
Y
V
E
L
K
T
A
K
E
M
H
R
P
Cat
Felis silvestris
Mouse
Mus musculus
O70348
397
45262
S249
A
P
C
T
Q
P
P
S
C
Y
V
E
L
K
T
Rat
Rattus norvegicus
Q6MG77
397
45281
S249
A
P
C
T
Q
P
P
S
C
Y
V
E
L
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512198
126
14180
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5HZT0
401
46175
D257
S
G
E
V
D
C
T
D
P
S
A
K
K
S
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10660
393
45840
D236
Y
A
V
V
F
R
N
D
L
Q
T
D
Q
R
L
Sea Urchin
Strong. purpuratus
XP_783738
649
73632
N263
S
K
K
K
P
P
E
N
Y
M
E
L
K
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RY73
544
60363
V379
A
N
V
E
F
C
S
V
V
R
T
K
L
G
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9HE87
383
44364
P231
K
P
R
T
Q
G
D
P
I
N
W
V
E
L
K
Conservation
Percent
Protein Identity:
100
99.2
60.6
77.5
N.A.
90.1
90.4
N.A.
23.4
N.A.
52.6
N.A.
N.A.
N.A.
N.A.
25.5
28.8
Protein Similarity:
100
99.4
62.3
81.3
N.A.
93.9
94.2
N.A.
29
N.A.
65.5
N.A.
N.A.
N.A.
N.A.
45.9
41.6
P-Site Identity:
100
100
6.6
6.6
N.A.
86.6
86.6
N.A.
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
100
100
20
20
N.A.
93.3
93.3
N.A.
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
N.A.
29.2
Protein Similarity:
N.A.
N.A.
N.A.
36.7
N.A.
43.4
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
9
0
0
0
0
0
0
9
0
9
0
0
0
9
% A
% Cys:
0
9
25
0
0
17
0
0
34
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
9
17
0
0
0
9
0
0
0
% D
% Glu:
0
0
9
9
9
9
9
0
0
0
17
42
9
0
0
% E
% Phe:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
9
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% I
% Lys:
9
9
9
9
0
0
9
9
0
9
9
17
17
34
9
% K
% Leu:
0
0
0
0
0
9
9
0
9
0
0
9
42
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
9
9
0
0
% M
% Asn:
0
9
0
0
0
0
9
9
0
9
0
0
0
0
0
% N
% Pro:
9
42
0
0
9
42
34
9
9
0
0
0
0
0
9
% P
% Gln:
0
0
0
0
42
0
0
0
0
9
0
0
9
0
0
% Q
% Arg:
0
0
9
0
0
9
0
0
0
9
0
0
0
17
0
% R
% Ser:
17
0
17
0
0
0
9
17
0
17
0
0
0
9
9
% S
% Thr:
9
9
0
42
0
0
9
25
9
0
17
0
0
9
42
% T
% Val:
0
0
17
25
9
0
0
9
9
0
34
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
9
0
9
9
0
0
0
0
9
34
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _