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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DOM3Z All Species: 18.79
Human Site: S163 Identified Species: 37.58
UniProt: O77932 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O77932 NP_005501.2 396 44929 S163 F Q G T L Y L S E V E T P N A
Chimpanzee Pan troglodytes XP_001161885 396 44867 S163 F Q G T L Y L S E V E T P N A
Rhesus Macaque Macaca mulatta XP_001106541 251 28178 Q28 E T P K A R A Q R L A R P P L
Dog Lupus familis XP_538842 347 39553 R124 T P A A R A Q R L A R P P L L
Cat Felis silvestris
Mouse Mus musculus O70348 397 45262 S163 F Q G T L Y L S E V E T P A A
Rat Rattus norvegicus Q6MG77 397 45281 S163 F Q G T L Y L S E V E T P A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512198 126 14180
Chicken Gallus gallus
Frog Xenopus laevis Q5HZT0 401 46175 T154 V T W R G H L T K I L C T P Y
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10660 393 45840 S153 G L I T K I C S T I Y N K E E
Sea Urchin Strong. purpuratus XP_783738 649 73632 S177 Y R G T Y Y I S E V E T E E N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RY73 544 60363 D276 L G S E G F G D L L G S I R A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q9HE87 383 44364 R148 Q A S R A N E R P W N G P I P
Conservation
Percent
Protein Identity: 100 99.2 60.6 77.5 N.A. 90.1 90.4 N.A. 23.4 N.A. 52.6 N.A. N.A. N.A. N.A. 25.5 28.8
Protein Similarity: 100 99.4 62.3 81.3 N.A. 93.9 94.2 N.A. 29 N.A. 65.5 N.A. N.A. N.A. N.A. 45.9 41.6
P-Site Identity: 100 100 6.6 6.6 N.A. 93.3 93.3 N.A. 0 N.A. 6.6 N.A. N.A. N.A. N.A. 13.3 53.3
P-Site Similarity: 100 100 13.3 6.6 N.A. 93.3 93.3 N.A. 0 N.A. 33.3 N.A. N.A. N.A. N.A. 20 73.3
Percent
Protein Identity: N.A. N.A. N.A. 22 N.A. 29.2
Protein Similarity: N.A. N.A. N.A. 36.7 N.A. 43.4
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 9 17 9 9 0 0 9 9 0 0 17 42 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 9 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % D
% Glu: 9 0 0 9 0 0 9 0 42 0 42 0 9 17 9 % E
% Phe: 34 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 9 42 0 17 0 9 0 0 0 9 9 0 0 0 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 0 9 9 0 0 17 0 0 9 9 0 % I
% Lys: 0 0 0 9 9 0 0 0 9 0 0 0 9 0 0 % K
% Leu: 9 9 0 0 34 0 42 0 17 17 9 0 0 9 17 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 9 9 0 17 9 % N
% Pro: 0 9 9 0 0 0 0 0 9 0 0 9 59 17 9 % P
% Gln: 9 34 0 0 0 0 9 9 0 0 0 0 0 0 0 % Q
% Arg: 0 9 0 17 9 9 0 17 9 0 9 9 0 9 0 % R
% Ser: 0 0 17 0 0 0 0 50 0 0 0 9 0 0 0 % S
% Thr: 9 17 0 50 0 0 0 9 9 0 0 42 9 0 0 % T
% Val: 9 0 0 0 0 0 0 0 0 42 0 0 0 0 0 % V
% Trp: 0 0 9 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 9 0 0 0 9 42 0 0 0 0 9 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _