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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOM3Z
All Species:
17.88
Human Site:
S154
Identified Species:
35.76
UniProt:
O77932
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O77932
NP_005501.2
396
44929
S154
E
G
W
Q
L
A
A
S
R
F
Q
G
T
L
Y
Chimpanzee
Pan troglodytes
XP_001161885
396
44867
S154
E
G
W
Q
L
A
A
S
R
F
Q
G
T
L
Y
Rhesus Macaque
Macaca mulatta
XP_001106541
251
28178
E19
T
G
T
L
Y
L
S
E
V
E
T
P
K
A
R
Dog
Lupus familis
XP_538842
347
39553
V115
G
T
L
Y
L
S
E
V
E
T
P
A
A
R
A
Cat
Felis silvestris
Mouse
Mus musculus
O70348
397
45262
S154
E
G
W
Q
L
A
A
S
R
F
Q
G
T
L
Y
Rat
Rattus norvegicus
Q6MG77
397
45281
S154
E
G
W
Q
L
A
A
S
R
F
Q
G
T
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512198
126
14180
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5HZT0
401
46175
D145
S
K
R
P
I
D
R
D
F
V
T
W
R
G
H
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10660
393
45840
W144
H
E
A
D
V
V
C
W
R
G
L
I
T
K
I
Sea Urchin
Strong. purpuratus
XP_783738
649
73632
T168
E
G
W
A
M
A
V
T
L
Y
R
G
T
Y
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RY73
544
60363
K267
Y
D
T
F
I
E
K
K
D
L
G
S
E
G
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9HE87
383
44364
Y139
F
I
E
E
N
H
A
Y
K
Q
A
S
R
A
N
Conservation
Percent
Protein Identity:
100
99.2
60.6
77.5
N.A.
90.1
90.4
N.A.
23.4
N.A.
52.6
N.A.
N.A.
N.A.
N.A.
25.5
28.8
Protein Similarity:
100
99.4
62.3
81.3
N.A.
93.9
94.2
N.A.
29
N.A.
65.5
N.A.
N.A.
N.A.
N.A.
45.9
41.6
P-Site Identity:
100
100
6.6
6.6
N.A.
100
100
N.A.
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
46.6
P-Site Similarity:
100
100
13.3
13.3
N.A.
100
100
N.A.
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
20
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
N.A.
29.2
Protein Similarity:
N.A.
N.A.
N.A.
36.7
N.A.
43.4
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
0
42
42
0
0
0
9
9
9
17
9
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
9
0
9
0
9
9
0
0
0
0
0
0
% D
% Glu:
42
9
9
9
0
9
9
9
9
9
0
0
9
0
0
% E
% Phe:
9
0
0
9
0
0
0
0
9
34
0
0
0
0
9
% F
% Gly:
9
50
0
0
0
0
0
0
0
9
9
42
0
17
0
% G
% His:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
9
0
0
17
0
0
0
0
0
0
9
0
0
9
% I
% Lys:
0
9
0
0
0
0
9
9
9
0
0
0
9
9
0
% K
% Leu:
0
0
9
9
42
9
0
0
9
9
9
0
0
34
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
9
0
0
0
0
0
0
9
9
0
0
0
% P
% Gln:
0
0
0
34
0
0
0
0
0
9
34
0
0
0
0
% Q
% Arg:
0
0
9
0
0
0
9
0
42
0
9
0
17
9
9
% R
% Ser:
9
0
0
0
0
9
9
34
0
0
0
17
0
0
0
% S
% Thr:
9
9
17
0
0
0
0
9
0
9
17
0
50
0
0
% T
% Val:
0
0
0
0
9
9
9
9
9
9
0
0
0
0
0
% V
% Trp:
0
0
42
0
0
0
0
9
0
0
0
9
0
0
0
% W
% Tyr:
9
0
0
9
9
0
0
9
0
9
0
0
0
9
42
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _