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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RSL1D1 All Species: 13.33
Human Site: T465 Identified Species: 20.95
UniProt: O76021 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O76021 NP_056474.2 490 54973 T465 P E A K F F T T P S K S V R K
Chimpanzee Pan troglodytes XP_001144836 490 54952 T465 P E A K F F T T P S K S V R K
Rhesus Macaque Macaca mulatta XP_001106695 487 54587 L463 G A R F F T T L S K S V R K A
Dog Lupus familis XP_536972 490 54892 T465 P G A R F F T T A N K S A K K
Cat Felis silvestris
Mouse Mus musculus NP_079822 452 50403 S428 K P E A S S F S T P R K S G K
Rat Rattus norvegicus NP_001008876 540 60945 V515 R R H W G G N V L G P K S V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517075 503 55446 T472 P E A R S F A T P N K G G R L
Chicken Gallus gallus P02259 190 20715 A166 V K A K S R K A S K A K K V K
Frog Xenopus laevis NP_001108267 318 35827 E294 S D A T I L D E G K S S S A E
Zebra Danio Brachydanio rerio XP_686114 373 42243 K349 V K K S V K D K K L V K K T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623930 327 38049 T303 G I A T V T V T P E G D I T V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795794 339 38444 K315 T P A K L V K K A K Q G S I G
Poplar Tree Populus trichocarpa XP_002321931 384 42954 L360 D G I K Q K K L K K G S L V S
Maize Zea mays NP_001146382 413 45597 M389 G E V G T E E M Q G D K K I K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191425 446 49952 K422 S K D G L K A K K T T M V A K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 93.6 68.3 N.A. 55.7 37.4 N.A. 39.1 23 36.1 36.1 N.A. N.A. 24.2 N.A. 27.9
Protein Similarity: 100 99.8 96.5 79.8 N.A. 72.2 52.2 N.A. 58.2 29.3 50 52.4 N.A. N.A. 38.5 N.A. 44.4
P-Site Identity: 100 100 13.3 60 N.A. 6.6 0 N.A. 53.3 20 13.3 0 N.A. N.A. 20 N.A. 13.3
P-Site Similarity: 100 100 20 80 N.A. 20 0 N.A. 66.6 26.6 26.6 6.6 N.A. N.A. 26.6 N.A. 20
Percent
Protein Identity: 24.6 26.1 N.A. 28.5 N.A. N.A.
Protein Similarity: 42.8 41.8 N.A. 46.1 N.A. N.A.
P-Site Identity: 13.3 13.3 N.A. 13.3 N.A. N.A.
P-Site Similarity: 20 13.3 N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 54 7 0 0 14 7 14 0 7 0 7 14 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 7 0 0 0 14 0 0 0 7 7 0 0 0 % D
% Glu: 0 27 7 0 0 7 7 7 0 7 0 0 0 0 7 % E
% Phe: 0 0 0 7 27 27 7 0 0 0 0 0 0 0 0 % F
% Gly: 20 14 0 14 7 7 0 0 7 14 14 14 7 7 7 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 7 0 7 0 0 0 0 0 0 0 7 14 0 % I
% Lys: 7 20 7 34 0 20 20 20 20 34 27 34 20 14 47 % K
% Leu: 0 0 0 0 14 7 0 14 7 7 0 0 7 0 7 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 7 0 0 0 % M
% Asn: 0 0 0 0 0 0 7 0 0 14 0 0 0 0 0 % N
% Pro: 27 14 0 0 0 0 0 0 27 7 7 0 0 0 7 % P
% Gln: 0 0 0 0 7 0 0 0 7 0 7 0 0 0 0 % Q
% Arg: 7 7 7 14 0 7 0 0 0 0 7 0 7 20 0 % R
% Ser: 14 0 0 7 20 7 0 7 14 14 14 34 27 0 7 % S
% Thr: 7 0 0 14 7 14 27 34 7 7 7 0 0 14 0 % T
% Val: 14 0 7 0 14 7 7 7 0 0 7 7 20 20 7 % V
% Trp: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _