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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RSL1D1 All Species: 10.91
Human Site: T358 Identified Species: 17.14
UniProt: O76021 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O76021 NP_056474.2 490 54973 T358 G K A Q V K A T N E S E D E I
Chimpanzee Pan troglodytes XP_001144836 490 54952 T358 G K A Q V K A T N E S E D E I
Rhesus Macaque Macaca mulatta XP_001106695 487 54587 T357 G K A Q V K A T D E S E D E I
Dog Lupus familis XP_536972 490 54892 K358 G K G K T Q Q K V Q D E S E D
Cat Felis silvestris
Mouse Mus musculus NP_079822 452 50403 A322 Q S G L A S S A P A K S P G A
Rat Rattus norvegicus NP_001008876 540 60945 S402 K Y L L S S T S S P R P W T G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517075 503 55446 G350 S T R Y L P L G R G K K A R I
Chicken Gallus gallus P02259 190 20715 K60 K Y I K S H Y K V G H N A D L
Frog Xenopus laevis NP_001108267 318 35827 G187 Q L H I N N K G C C Y S I R V
Zebra Danio Brachydanio rerio XP_686114 373 42243 L243 K N I K I I H L K S Q T S V A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623930 327 38049 R197 H E I E Y A L R K T V M Q I H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795794 339 38444 I209 A K D I T D N I L S A V T S L
Poplar Tree Populus trichocarpa XP_002321931 384 42954 D254 P V Y Q V V P D S K L K I D G
Maize Zea mays NP_001146382 413 45597 D283 K K I D K K G D A G A R G R E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191425 446 49952 Y316 G R I H E V R Y M D S N V A E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 93.6 68.3 N.A. 55.7 37.4 N.A. 39.1 23 36.1 36.1 N.A. N.A. 24.2 N.A. 27.9
Protein Similarity: 100 99.8 96.5 79.8 N.A. 72.2 52.2 N.A. 58.2 29.3 50 52.4 N.A. N.A. 38.5 N.A. 44.4
P-Site Identity: 100 100 93.3 26.6 N.A. 0 0 N.A. 6.6 0 0 0 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 100 100 46.6 N.A. 6.6 13.3 N.A. 20 20 6.6 13.3 N.A. N.A. 13.3 N.A. 20
Percent
Protein Identity: 24.6 26.1 N.A. 28.5 N.A. N.A.
Protein Similarity: 42.8 41.8 N.A. 46.1 N.A. N.A.
P-Site Identity: 13.3 13.3 N.A. 13.3 N.A. N.A.
P-Site Similarity: 40 20 N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 20 0 7 7 20 7 7 7 14 0 14 7 14 % A
% Cys: 0 0 0 0 0 0 0 0 7 7 0 0 0 0 0 % C
% Asp: 0 0 7 7 0 7 0 14 7 7 7 0 20 14 7 % D
% Glu: 0 7 0 7 7 0 0 0 0 20 0 27 0 27 14 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 34 0 14 0 0 0 7 14 0 20 0 0 7 7 14 % G
% His: 7 0 7 7 0 7 7 0 0 0 7 0 0 0 7 % H
% Ile: 0 0 34 14 7 7 0 7 0 0 0 0 14 7 27 % I
% Lys: 27 40 0 20 7 27 7 14 14 7 14 14 0 0 0 % K
% Leu: 0 7 7 14 7 0 14 7 7 0 7 0 0 0 14 % L
% Met: 0 0 0 0 0 0 0 0 7 0 0 7 0 0 0 % M
% Asn: 0 7 0 0 7 7 7 0 14 0 0 14 0 0 0 % N
% Pro: 7 0 0 0 0 7 7 0 7 7 0 7 7 0 0 % P
% Gln: 14 0 0 27 0 7 7 0 0 7 7 0 7 0 0 % Q
% Arg: 0 7 7 0 0 0 7 7 7 0 7 7 0 20 0 % R
% Ser: 7 7 0 0 14 14 7 7 14 14 27 14 14 7 0 % S
% Thr: 0 7 0 0 14 0 7 20 0 7 0 7 7 7 0 % T
% Val: 0 7 0 0 27 14 0 0 14 0 7 7 7 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % W
% Tyr: 0 14 7 7 7 0 7 7 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _