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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RSL1D1 All Species: 12.42
Human Site: S49 Identified Species: 19.52
UniProt: O76021 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O76021 NP_056474.2 490 54973 S49 A L L T H C K S R K N N Y G L
Chimpanzee Pan troglodytes XP_001144836 490 54952 S49 A L L T H C K S R K N N Y G L
Rhesus Macaque Macaca mulatta XP_001106695 487 54587 S49 A L L T H C K S R K N N Y G L
Dog Lupus familis XP_536972 490 54892 S47 A L L A H S R S R K N A N G L
Cat Felis silvestris
Mouse Mus musculus NP_079822 452 50403 V42 Q I R K A V E V I S N R S K S
Rat Rattus norvegicus NP_001008876 540 60945 V65 I L S E S S E V C L F T K D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517075 503 55446 N45 H P G I Q K N N L L L S D Y E
Chicken Gallus gallus P02259 190 20715
Frog Xenopus laevis NP_001108267 318 35827
Zebra Danio Brachydanio rerio XP_686114 373 42243
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623930 327 38049
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795794 339 38444
Poplar Tree Populus trichocarpa XP_002321931 384 42954
Maize Zea mays NP_001146382 413 45597
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191425 446 49952 L36 V E S A L N G L I N W R S D K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 93.6 68.3 N.A. 55.7 37.4 N.A. 39.1 23 36.1 36.1 N.A. N.A. 24.2 N.A. 27.9
Protein Similarity: 100 99.8 96.5 79.8 N.A. 72.2 52.2 N.A. 58.2 29.3 50 52.4 N.A. N.A. 38.5 N.A. 44.4
P-Site Identity: 100 100 100 66.6 N.A. 6.6 6.6 N.A. 0 0 0 0 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 100 100 73.3 N.A. 20 13.3 N.A. 13.3 0 0 0 N.A. N.A. 0 N.A. 0
Percent
Protein Identity: 24.6 26.1 N.A. 28.5 N.A. N.A.
Protein Similarity: 42.8 41.8 N.A. 46.1 N.A. N.A.
P-Site Identity: 0 0 N.A. 0 N.A. N.A.
P-Site Similarity: 0 0 N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 27 0 0 14 7 0 0 0 0 0 0 7 0 0 0 % A
% Cys: 0 0 0 0 0 20 0 0 7 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 7 14 0 % D
% Glu: 0 7 0 7 0 0 14 0 0 0 0 0 0 0 14 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % F
% Gly: 0 0 7 0 0 0 7 0 0 0 0 0 0 27 0 % G
% His: 7 0 0 0 27 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 7 0 7 0 0 0 0 14 0 0 0 0 0 0 % I
% Lys: 0 0 0 7 0 7 20 0 0 27 0 0 7 7 7 % K
% Leu: 0 34 27 0 7 0 0 7 7 14 7 0 0 0 27 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 7 7 7 0 7 34 20 7 0 0 % N
% Pro: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 7 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 7 0 0 0 7 0 27 0 0 14 0 0 0 % R
% Ser: 0 0 14 0 7 14 0 27 0 7 0 7 14 0 7 % S
% Thr: 0 0 0 20 0 0 0 0 0 0 0 7 0 0 0 % T
% Val: 7 0 0 0 0 7 0 14 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 20 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _