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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RSL1D1
All Species:
7.58
Human Site:
S427
Identified Species:
11.9
UniProt:
O76021
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O76021
NP_056474.2
490
54973
S427
E
S
E
T
P
G
K
S
P
E
K
K
P
K
I
Chimpanzee
Pan troglodytes
XP_001144836
490
54952
S427
E
S
E
T
P
G
K
S
P
E
K
K
P
K
I
Rhesus Macaque
Macaca mulatta
XP_001106695
487
54587
G426
E
T
P
G
K
G
P
G
K
K
R
K
I
K
E
Dog
Lupus familis
XP_536972
490
54892
G427
E
A
K
T
P
G
N
G
P
E
K
K
P
R
I
Cat
Felis silvestris
Mouse
Mus musculus
NP_079822
452
50403
R391
S
T
P
K
G
K
K
R
K
A
L
L
A
T
E
Rat
Rattus norvegicus
NP_001008876
540
60945
T471
Q
A
G
V
N
T
V
T
T
S
V
E
N
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517075
503
55446
T419
G
K
A
T
R
R
R
T
P
R
K
P
E
A
S
Chicken
Gallus gallus
P02259
190
20715
R129
A
A
R
P
R
K
A
R
S
P
A
K
K
P
K
Frog
Xenopus laevis
NP_001108267
318
35827
L256
L
H
E
L
N
L
S
L
K
K
T
K
N
K
K
Zebra Danio
Brachydanio rerio
XP_686114
373
42243
P312
E
E
I
P
Q
L
V
P
I
E
T
P
K
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623930
327
38049
K266
L
P
I
Y
M
T
L
K
N
K
C
L
V
D
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795794
339
38444
K278
K
Q
M
R
F
E
A
K
E
A
A
K
K
D
P
Poplar Tree
Populus trichocarpa
XP_002321931
384
42954
D323
E
V
E
L
G
S
D
D
N
K
G
K
G
E
K
Maize
Zea mays
NP_001146382
413
45597
E352
K
K
G
K
R
G
L
E
N
K
V
N
E
A
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_191425
446
49952
K385
K
P
M
K
K
A
A
K
G
K
S
K
P
D
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
93.6
68.3
N.A.
55.7
37.4
N.A.
39.1
23
36.1
36.1
N.A.
N.A.
24.2
N.A.
27.9
Protein Similarity:
100
99.8
96.5
79.8
N.A.
72.2
52.2
N.A.
58.2
29.3
50
52.4
N.A.
N.A.
38.5
N.A.
44.4
P-Site Identity:
100
100
26.6
66.6
N.A.
6.6
0
N.A.
20
6.6
20
20
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
46.6
86.6
N.A.
13.3
33.3
N.A.
33.3
13.3
26.6
20
N.A.
N.A.
13.3
N.A.
13.3
Percent
Protein Identity:
24.6
26.1
N.A.
28.5
N.A.
N.A.
Protein Similarity:
42.8
41.8
N.A.
46.1
N.A.
N.A.
P-Site Identity:
20
6.6
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
33.3
20
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
20
7
0
0
7
20
0
0
14
14
0
7
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
7
7
0
0
0
0
0
20
0
% D
% Glu:
40
7
27
0
0
7
0
7
7
27
0
7
14
7
14
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
14
7
14
34
0
14
7
0
7
0
7
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
14
0
0
0
0
0
7
0
0
0
7
0
20
% I
% Lys:
20
14
7
20
14
14
20
20
20
40
27
60
20
34
34
% K
% Leu:
14
0
0
14
0
14
14
7
0
0
7
14
0
0
0
% L
% Met:
0
0
14
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
14
0
7
0
20
0
0
7
14
0
0
% N
% Pro:
0
14
14
14
20
0
7
7
27
7
0
14
27
7
7
% P
% Gln:
7
7
0
0
7
0
0
0
0
0
0
0
0
7
0
% Q
% Arg:
0
0
7
7
20
7
7
14
0
7
7
0
0
7
0
% R
% Ser:
7
14
0
0
0
7
7
14
7
7
7
0
0
0
14
% S
% Thr:
0
14
0
27
0
14
0
14
7
0
14
0
0
7
0
% T
% Val:
0
7
0
7
0
0
14
0
0
0
14
0
7
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _