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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS2
All Species:
17.27
Human Site:
Y154
Identified Species:
31.67
UniProt:
O75928
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75928
NP_004662.2
621
68240
Y154
Q
L
K
N
L
P
F
Y
D
V
L
D
V
L
I
Chimpanzee
Pan troglodytes
XP_001147441
612
67116
D146
L
K
N
L
P
F
Y
D
V
L
D
V
L
I
K
Rhesus Macaque
Macaca mulatta
XP_001085703
612
67146
D146
L
K
N
L
P
F
Y
D
V
L
D
V
L
I
K
Dog
Lupus familis
XP_852829
541
60303
S84
D
V
T
P
H
S
P
S
S
P
V
G
S
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5D8
621
68407
Y154
Q
L
K
N
L
P
F
Y
D
V
L
D
V
L
I
Rat
Rattus norvegicus
Q6AZ28
572
63413
S115
S
I
A
P
H
S
P
S
S
P
V
A
S
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506015
622
68325
Y154
Q
L
K
S
L
P
F
Y
D
V
L
D
V
L
I
Chicken
Gallus gallus
NP_001025797
622
68442
Y154
Q
L
K
S
L
P
F
Y
D
V
L
D
V
L
I
Frog
Xenopus laevis
NP_001084972
584
64427
K126
S
V
L
L
Q
D
T
K
A
P
F
E
I
Q
Q
Zebra Danio
Brachydanio rerio
XP_685704
623
69106
D153
M
K
S
L
P
F
Y
D
V
L
D
V
L
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
D237
P
L
P
L
P
F
Y
D
V
I
S
V
L
L
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
D171
I
C
R
L
T
R
A
D
P
F
W
V
T
V
A
Baker's Yeast
Sacchar. cerevisiae
Q12216
726
81160
S153
Q
Q
Q
A
L
A
Y
S
F
T
S
P
F
Y
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
98.3
84
N.A.
98
87.5
N.A.
93.8
92.4
74.7
71.5
N.A.
N.A.
N.A.
23.4
N.A.
Protein Similarity:
100
98.5
98.3
85.6
N.A.
99
90
N.A.
97.1
95.8
84.2
83.3
N.A.
N.A.
N.A.
39.8
N.A.
P-Site Identity:
100
0
0
0
N.A.
100
0
N.A.
93.3
93.3
0
0
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
26.6
26.6
26.6
N.A.
100
26.6
N.A.
100
100
20
26.6
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.8
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
8
8
0
8
0
0
8
0
0
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
0
39
31
0
24
31
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
31
31
0
8
8
8
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
0
0
8
0
0
8
24
31
% I
% Lys:
0
24
31
0
0
0
0
8
0
0
0
0
0
0
39
% K
% Leu:
16
39
8
47
39
0
0
0
0
24
31
0
31
39
16
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
16
16
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
8
16
31
31
16
0
8
24
0
8
0
0
0
% P
% Gln:
39
8
8
0
8
0
0
0
0
0
0
0
0
8
8
% Q
% Arg:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
16
0
8
16
0
16
0
24
16
0
16
0
16
0
0
% S
% Thr:
0
0
8
0
8
0
8
0
0
8
0
0
8
0
0
% T
% Val:
0
16
0
0
0
0
0
0
31
31
16
39
31
24
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
39
31
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _