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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIAS2 All Species: 31.52
Human Site: T264 Identified Species: 57.78
UniProt: O75928 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75928 NP_004662.2 621 68240 T264 P G R P L N I T S L V R L S S
Chimpanzee Pan troglodytes XP_001147441 612 67116 T255 P G R P L N I T S L V R L S S
Rhesus Macaque Macaca mulatta XP_001085703 612 67146 T255 P G R P L N I T S L V R L S S
Dog Lupus familis XP_852829 541 60303 C189 L C L A E T S C P Q E D N Y P
Cat Felis silvestris
Mouse Mus musculus Q8C5D8 621 68407 T264 P G R P L N I T S L V R L S S
Rat Rattus norvegicus Q6AZ28 572 63413 C220 L C L A E T S C P Q E D N Y P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506015 622 68325 T264 P G R P L N I T S L V R L S S
Chicken Gallus gallus NP_001025797 622 68442 T264 P G R P L N I T S L V R L S S
Frog Xenopus laevis NP_001084972 584 64427 I231 N Y P S S L C I K V N G K L F
Zebra Danio Brachydanio rerio XP_685704 623 69106 T263 P G R P L N I T S L V R L S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q94361 793 89556 N345 K R P S R P V N I T S N M N R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q680Q4 884 97015 T276 R D D G P I I T S C I R D G V
Baker's Yeast Sacchar. cerevisiae Q12216 726 81160 T258 T G N P A N L T P Y L K V P T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 98.3 84 N.A. 98 87.5 N.A. 93.8 92.4 74.7 71.5 N.A. N.A. N.A. 23.4 N.A.
Protein Similarity: 100 98.5 98.3 85.6 N.A. 99 90 N.A. 97.1 95.8 84.2 83.3 N.A. N.A. N.A. 39.8 N.A.
P-Site Identity: 100 100 100 0 N.A. 100 0 N.A. 100 100 0 100 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 100 0 N.A. 100 0 N.A. 100 100 6.6 100 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.3 20.1 N.A.
Protein Similarity: N.A. N.A. N.A. 34.8 38.5 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 16 8 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 16 0 0 0 0 8 16 0 8 0 0 0 0 0 % C
% Asp: 0 8 8 0 0 0 0 0 0 0 0 16 8 0 0 % D
% Glu: 0 0 0 0 16 0 0 0 0 0 16 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 0 62 0 8 0 0 0 0 0 0 0 8 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 62 8 8 0 8 0 0 0 0 % I
% Lys: 8 0 0 0 0 0 0 0 8 0 0 8 8 0 0 % K
% Leu: 16 0 16 0 54 8 8 0 0 54 8 0 54 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 8 0 8 0 0 62 0 8 0 0 8 8 16 8 0 % N
% Pro: 54 0 16 62 8 8 0 0 24 0 0 0 0 8 16 % P
% Gln: 0 0 0 0 0 0 0 0 0 16 0 0 0 0 0 % Q
% Arg: 8 8 54 0 8 0 0 0 0 0 0 62 0 0 8 % R
% Ser: 0 0 0 16 8 0 16 0 62 0 8 0 0 54 54 % S
% Thr: 8 0 0 0 0 16 0 70 0 8 0 0 0 0 8 % T
% Val: 0 0 0 0 0 0 8 0 0 8 54 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 8 0 0 0 16 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _