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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS2
All Species:
13.64
Human Site:
T206
Identified Species:
25
UniProt:
O75928
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75928
NP_004662.2
621
68240
T206
P
G
G
R
R
D
Y
T
V
Q
V
Q
L
R
L
Chimpanzee
Pan troglodytes
XP_001147441
612
67116
V198
G
G
R
R
D
Y
T
V
Q
V
Q
L
R
L
C
Rhesus Macaque
Macaca mulatta
XP_001085703
612
67146
V198
G
G
R
R
D
Y
T
V
Q
V
Q
L
R
L
C
Dog
Lupus familis
XP_852829
541
60303
V136
L
I
K
P
T
S
L
V
Q
S
S
I
Q
R
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5D8
621
68407
T206
P
G
G
R
R
D
Y
T
V
Q
V
Q
L
R
L
Rat
Rattus norvegicus
Q6AZ28
572
63413
V167
L
I
K
P
T
S
L
V
Q
S
S
I
Q
R
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506015
622
68325
T206
P
G
G
R
R
D
Y
T
V
Q
V
Q
L
R
L
Chicken
Gallus gallus
NP_001025797
622
68442
T206
P
G
G
R
R
D
Y
T
V
Q
V
Q
L
R
L
Frog
Xenopus laevis
NP_001084972
584
64427
F178
Q
R
F
Q
E
K
F
F
I
F
A
L
T
P
Q
Zebra Danio
Brachydanio rerio
XP_685704
623
69106
M205
P
G
G
R
R
D
Y
M
V
Q
I
Q
L
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
E289
V
T
P
L
P
R
Y
E
L
Q
L
R
F
F
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
V223
L
A
K
P
E
Y
D
V
Q
A
W
C
M
L
L
Baker's Yeast
Sacchar. cerevisiae
Q12216
726
81160
L205
N
K
S
Y
K
L
Y
L
F
S
G
F
S
I
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
98.3
84
N.A.
98
87.5
N.A.
93.8
92.4
74.7
71.5
N.A.
N.A.
N.A.
23.4
N.A.
Protein Similarity:
100
98.5
98.3
85.6
N.A.
99
90
N.A.
97.1
95.8
84.2
83.3
N.A.
N.A.
N.A.
39.8
N.A.
P-Site Identity:
100
13.3
13.3
6.6
N.A.
100
6.6
N.A.
100
100
0
80
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
13.3
13.3
6.6
N.A.
100
6.6
N.A.
100
100
20
86.6
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.8
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
16
% C
% Asp:
0
0
0
0
16
39
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
16
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
8
8
8
8
0
8
8
8
24
% F
% Gly:
16
54
39
0
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
0
0
0
0
0
8
0
8
16
0
8
0
% I
% Lys:
0
8
24
0
8
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
24
0
0
8
0
8
16
8
8
0
8
24
39
24
39
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
39
0
8
24
8
0
0
0
0
0
0
0
0
8
8
% P
% Gln:
8
0
0
8
0
0
0
0
39
47
16
39
16
0
8
% Q
% Arg:
0
8
16
54
39
8
0
0
0
0
0
8
16
54
0
% R
% Ser:
0
0
8
0
0
16
0
0
0
24
16
0
8
0
0
% S
% Thr:
0
8
0
0
16
0
16
31
0
0
0
0
8
0
0
% T
% Val:
8
0
0
0
0
0
0
39
39
16
31
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
8
0
24
54
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _