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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS2
All Species:
16.97
Human Site:
S596
Identified Species:
31.11
UniProt:
O75928
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75928
NP_004662.2
621
68240
S596
H
E
S
S
T
H
V
S
S
S
S
S
R
S
E
Chimpanzee
Pan troglodytes
XP_001147441
612
67116
S587
H
E
S
S
T
H
V
S
S
S
S
S
R
S
E
Rhesus Macaque
Macaca mulatta
XP_001085703
612
67146
S587
H
E
S
S
T
H
V
S
S
S
S
S
R
S
E
Dog
Lupus familis
XP_852829
541
60303
L517
I
S
S
M
S
S
D
L
P
G
E
Q
R
R
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5D8
621
68407
S596
H
E
S
S
T
H
V
S
S
S
S
S
R
S
E
Rat
Rattus norvegicus
Q6AZ28
572
63413
L548
V
S
S
M
S
S
D
L
P
G
E
Q
R
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506015
622
68325
H596
S
P
H
E
S
T
T
H
V
S
S
S
S
R
S
Chicken
Gallus gallus
NP_001025797
622
68442
H596
S
H
H
E
S
N
T
H
V
S
S
S
N
R
S
Frog
Xenopus laevis
NP_001084972
584
64427
D559
F
L
S
L
V
S
M
D
P
Q
Y
Y
P
P
M
Zebra Danio
Brachydanio rerio
XP_685704
623
69106
A596
S
S
A
Q
Y
E
T
A
T
H
S
S
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
T692
L
V
Q
L
H
H
T
T
H
P
L
N
F
A
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
G819
H
Q
M
S
T
R
E
G
S
M
D
T
T
T
E
Baker's Yeast
Sacchar. cerevisiae
Q12216
726
81160
S658
L
P
P
Y
I
H
V
S
T
S
G
H
G
D
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
98.3
84
N.A.
98
87.5
N.A.
93.8
92.4
74.7
71.5
N.A.
N.A.
N.A.
23.4
N.A.
Protein Similarity:
100
98.5
98.3
85.6
N.A.
99
90
N.A.
97.1
95.8
84.2
83.3
N.A.
N.A.
N.A.
39.8
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
100
13.3
N.A.
20
20
6.6
20
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
20
N.A.
26.6
33.3
13.3
40
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.8
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
8
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
16
8
0
0
8
0
0
8
8
% D
% Glu:
0
31
0
16
0
8
8
0
0
0
16
0
0
0
39
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
16
8
0
8
0
0
% G
% His:
39
8
16
0
8
47
0
16
8
8
0
8
0
0
0
% H
% Ile:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
16
8
0
16
0
0
0
16
0
0
8
0
0
0
0
% L
% Met:
0
0
8
16
0
0
8
0
0
8
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
8
8
0
16
% N
% Pro:
0
16
8
0
0
0
0
0
24
8
0
0
8
8
0
% P
% Gln:
0
8
8
8
0
0
0
0
0
8
0
16
0
0
8
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
47
31
0
% R
% Ser:
24
24
54
39
31
24
0
39
39
54
54
54
16
39
24
% S
% Thr:
0
0
0
0
39
8
31
8
16
0
0
8
8
8
0
% T
% Val:
8
8
0
0
8
0
39
0
16
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
0
0
0
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _