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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS2
All Species:
28.48
Human Site:
S543
Identified Species:
52.22
UniProt:
O75928
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75928
NP_004662.2
621
68240
S543
F
H
H
T
P
I
S
S
M
S
S
D
L
P
G
Chimpanzee
Pan troglodytes
XP_001147441
612
67116
S534
F
H
H
T
P
I
S
S
M
S
S
D
L
P
G
Rhesus Macaque
Macaca mulatta
XP_001085703
612
67146
S534
F
H
H
T
P
I
S
S
M
S
S
D
L
P
G
Dog
Lupus familis
XP_852829
541
60303
E464
R
K
C
I
F
M
S
E
T
Q
S
S
P
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5D8
621
68407
S543
F
H
H
T
P
V
S
S
M
S
S
D
L
P
G
Rat
Rattus norvegicus
Q6AZ28
572
63413
E495
R
K
C
I
F
M
S
E
T
Q
S
S
P
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506015
622
68325
S543
F
H
H
T
P
V
S
S
I
S
S
D
L
P
G
Chicken
Gallus gallus
NP_001025797
622
68442
S543
F
H
H
P
P
M
S
S
I
S
S
D
L
P
G
Frog
Xenopus laevis
NP_001084972
584
64427
Y506
A
M
K
G
V
L
S
Y
Q
P
S
S
I
R
V
Zebra Danio
Brachydanio rerio
XP_685704
623
69106
T543
F
H
H
S
S
L
S
T
I
P
T
D
M
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
Q639
R
Q
M
S
Q
Q
N
Q
M
P
V
G
S
S
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
S766
L
P
T
K
P
D
A
S
A
Q
S
G
F
K
N
Baker's Yeast
Sacchar. cerevisiae
Q12216
726
81160
Y605
T
E
A
Q
R
N
P
Y
G
P
N
Y
N
T
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
98.3
84
N.A.
98
87.5
N.A.
93.8
92.4
74.7
71.5
N.A.
N.A.
N.A.
23.4
N.A.
Protein Similarity:
100
98.5
98.3
85.6
N.A.
99
90
N.A.
97.1
95.8
84.2
83.3
N.A.
N.A.
N.A.
39.8
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
93.3
13.3
N.A.
86.6
80
13.3
33.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
20
N.A.
100
93.3
26.6
73.3
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.8
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
8
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
54
0
0
0
% D
% Glu:
0
8
0
0
0
0
0
16
0
0
0
0
0
0
0
% E
% Phe:
54
0
0
0
16
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
8
0
0
16
0
0
47
% G
% His:
0
54
54
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
16
0
24
0
0
24
0
0
0
8
0
0
% I
% Lys:
0
16
8
8
0
0
0
0
0
0
0
0
0
8
16
% K
% Leu:
8
0
0
0
0
16
0
0
0
0
0
0
47
0
0
% L
% Met:
0
8
8
0
0
24
0
0
39
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
8
8
0
0
0
8
0
8
0
8
% N
% Pro:
0
8
0
8
54
0
8
0
0
31
0
0
16
47
8
% P
% Gln:
0
8
0
8
8
8
0
8
8
24
0
0
0
8
0
% Q
% Arg:
24
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
0
0
16
8
0
77
54
0
47
77
24
8
8
8
% S
% Thr:
8
0
8
39
0
0
0
8
16
0
8
0
0
24
8
% T
% Val:
0
0
0
0
8
16
0
0
0
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
16
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _