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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIAS2 All Species: 28.48
Human Site: S478 Identified Species: 52.22
UniProt: O75928 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75928 NP_004662.2 621 68240 S478 D L T I E S S S D E E E D P P
Chimpanzee Pan troglodytes XP_001147441 612 67116 S469 D L T I E S S S D E E E D P P
Rhesus Macaque Macaca mulatta XP_001085703 612 67146 S469 D L T I E S S S D E E E D P P
Dog Lupus familis XP_852829 541 60303 K400 W C P M R P K K E A M K V S S
Cat Felis silvestris
Mouse Mus musculus Q8C5D8 621 68407 S478 D L T I E S S S D E E E D P P
Rat Rattus norvegicus Q6AZ28 572 63413 K431 W C P M R P K K E A M K V T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506015 622 68325 S478 D L T I E S S S D E E E E P P
Chicken Gallus gallus NP_001025797 622 68442 S478 D L T I E S S S D E E E D P P
Frog Xenopus laevis NP_001084972 584 64427 H442 S P N T Q Y P H I E G T G V I
Zebra Danio Brachydanio rerio XP_685704 623 69106 S477 D L T L E S S S D D E E D D P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q94361 793 89556 T560 P A D D D I I T L S D D D D E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q680Q4 884 97015 G495 K Q E G Y S D G P A P L K L G
Baker's Yeast Sacchar. cerevisiae Q12216 726 81160 P470 N G S N H N E P E I I S L D S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 98.3 84 N.A. 98 87.5 N.A. 93.8 92.4 74.7 71.5 N.A. N.A. N.A. 23.4 N.A.
Protein Similarity: 100 98.5 98.3 85.6 N.A. 99 90 N.A. 97.1 95.8 84.2 83.3 N.A. N.A. N.A. 39.8 N.A.
P-Site Identity: 100 100 100 0 N.A. 100 0 N.A. 93.3 100 6.6 80 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 20 N.A. 100 20 N.A. 100 100 13.3 93.3 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.3 20.1 N.A.
Protein Similarity: N.A. N.A. N.A. 34.8 38.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 24 0 0 0 0 0 % A
% Cys: 0 16 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 54 0 8 8 8 0 8 0 54 8 8 8 54 24 0 % D
% Glu: 0 0 8 0 54 0 8 0 24 54 54 54 8 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 8 0 0 0 8 0 0 8 0 8 0 8 % G
% His: 0 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 47 0 8 8 0 8 8 8 0 0 0 8 % I
% Lys: 8 0 0 0 0 0 16 16 0 0 0 16 8 0 0 % K
% Leu: 0 54 0 8 0 0 0 0 8 0 0 8 8 8 0 % L
% Met: 0 0 0 16 0 0 0 0 0 0 16 0 0 0 0 % M
% Asn: 8 0 8 8 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 8 16 0 0 16 8 8 8 0 8 0 0 47 54 % P
% Gln: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 16 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 0 8 0 0 62 54 54 0 8 0 8 0 8 24 % S
% Thr: 0 0 54 8 0 0 0 8 0 0 0 8 0 8 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 16 8 0 % V
% Trp: 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _