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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS2
All Species:
22.42
Human Site:
S448
Identified Species:
41.11
UniProt:
O75928
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75928
NP_004662.2
621
68240
S448
C
T
K
I
E
S
S
S
V
L
S
K
P
C
S
Chimpanzee
Pan troglodytes
XP_001147441
612
67116
S439
C
T
K
I
E
S
S
S
V
L
S
K
P
C
S
Rhesus Macaque
Macaca mulatta
XP_001085703
612
67146
S439
C
T
K
I
E
S
S
S
V
L
S
K
P
C
S
Dog
Lupus familis
XP_852829
541
60303
G370
Y
E
S
L
I
L
D
G
L
F
M
E
I
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5D8
621
68407
S448
C
T
K
V
E
S
S
S
V
F
S
K
P
C
S
Rat
Rattus norvegicus
Q6AZ28
572
63413
G401
Y
E
S
L
I
L
D
G
L
F
M
E
I
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506015
622
68325
S448
C
T
K
I
E
S
S
S
V
L
S
K
P
C
S
Chicken
Gallus gallus
NP_001025797
622
68442
S448
C
T
K
I
E
S
S
S
V
V
S
K
P
C
S
Frog
Xenopus laevis
NP_001084972
584
64427
V412
I
L
N
Q
C
S
D
V
D
E
I
K
F
Q
Q
Zebra Danio
Brachydanio rerio
XP_685704
623
69106
V447
I
S
K
I
D
C
S
V
P
V
R
Q
S
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
V530
D
D
V
V
P
A
T
V
N
G
T
A
S
C
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
H465
L
G
E
L
S
Q
W
H
A
P
D
G
S
L
C
Baker's Yeast
Sacchar. cerevisiae
Q12216
726
81160
E440
Q
N
H
S
V
K
N
E
N
Q
G
T
V
K
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
98.3
84
N.A.
98
87.5
N.A.
93.8
92.4
74.7
71.5
N.A.
N.A.
N.A.
23.4
N.A.
Protein Similarity:
100
98.5
98.3
85.6
N.A.
99
90
N.A.
97.1
95.8
84.2
83.3
N.A.
N.A.
N.A.
39.8
N.A.
P-Site Identity:
100
100
100
0
N.A.
86.6
0
N.A.
100
93.3
13.3
20
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
93.3
26.6
N.A.
100
100
13.3
46.6
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.8
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
8
0
0
8
0
8
0
% A
% Cys:
47
0
0
0
8
8
0
0
0
0
0
0
0
54
8
% C
% Asp:
8
8
0
0
8
0
24
0
8
0
8
0
0
0
0
% D
% Glu:
0
16
8
0
47
0
0
8
0
8
0
16
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
24
0
0
8
0
0
% F
% Gly:
0
8
0
0
0
0
0
16
0
8
8
8
0
0
0
% G
% His:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
16
0
0
47
16
0
0
0
0
0
8
0
16
0
0
% I
% Lys:
0
0
54
0
0
8
0
0
0
0
0
54
0
8
0
% K
% Leu:
8
8
0
24
0
16
0
0
16
31
0
0
0
24
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
8
0
16
0
0
0
0
0
16
% N
% Pro:
0
0
0
0
8
0
0
0
8
8
0
0
47
0
0
% P
% Gln:
8
0
0
8
0
8
0
0
0
8
0
8
0
8
16
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
8
16
8
8
54
54
47
0
0
47
0
24
0
54
% S
% Thr:
0
47
0
0
0
0
8
0
0
0
8
8
0
0
0
% T
% Val:
0
0
8
16
8
0
0
24
47
16
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _