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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS2
All Species:
18.79
Human Site:
S194
Identified Species:
34.44
UniProt:
O75928
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75928
NP_004662.2
621
68240
S194
Q
V
R
E
I
C
I
S
R
D
F
L
P
G
G
Chimpanzee
Pan troglodytes
XP_001147441
612
67116
R186
V
R
E
I
C
I
S
R
D
F
L
P
G
G
R
Rhesus Macaque
Macaca mulatta
XP_001085703
612
67146
R186
V
R
E
I
C
I
S
R
D
F
L
P
G
G
R
Dog
Lupus familis
XP_852829
541
60303
D124
L
K
N
L
P
F
Y
D
V
L
D
V
L
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5D8
621
68407
S194
Q
V
R
E
I
C
I
S
R
D
F
L
P
G
G
Rat
Rattus norvegicus
Q6AZ28
572
63413
D155
L
K
T
L
P
F
Y
D
V
L
D
V
L
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506015
622
68325
S194
Q
V
R
E
I
C
I
S
R
D
F
L
P
G
G
Chicken
Gallus gallus
NP_001025797
622
68442
S194
Q
V
R
E
I
C
I
S
R
D
F
L
P
G
G
Frog
Xenopus laevis
NP_001084972
584
64427
V166
L
V
K
P
T
S
L
V
Q
N
S
L
Q
R
F
Zebra Danio
Brachydanio rerio
XP_685704
623
69106
S193
Q
V
R
E
V
C
I
S
R
D
F
L
P
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
S277
A
E
H
I
S
K
I
S
Y
R
A
D
V
T
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
A211
R
T
F
Q
I
T
R
A
D
K
D
L
L
A
K
Baker's Yeast
Sacchar. cerevisiae
Q12216
726
81160
D193
K
V
S
K
S
N
H
D
L
L
K
S
N
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
98.3
84
N.A.
98
87.5
N.A.
93.8
92.4
74.7
71.5
N.A.
N.A.
N.A.
23.4
N.A.
Protein Similarity:
100
98.5
98.3
85.6
N.A.
99
90
N.A.
97.1
95.8
84.2
83.3
N.A.
N.A.
N.A.
39.8
N.A.
P-Site Identity:
100
6.6
6.6
0
N.A.
100
0
N.A.
100
100
13.3
93.3
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
6.6
6.6
6.6
N.A.
100
6.6
N.A.
100
100
40
100
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.8
38.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
8
0
0
8
0
0
8
0
% A
% Cys:
0
0
0
0
16
39
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
24
24
39
24
8
0
0
0
% D
% Glu:
0
8
16
39
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
16
0
0
0
16
39
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
16
54
39
% G
% His:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
24
39
16
47
0
0
0
0
0
0
16
0
% I
% Lys:
8
16
8
8
0
8
0
0
0
8
8
0
0
8
24
% K
% Leu:
24
0
0
16
0
0
8
0
8
24
16
54
24
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
0
0
8
0
0
8
0
0
% N
% Pro:
0
0
0
8
16
0
0
0
0
0
0
16
39
0
8
% P
% Gln:
39
0
0
8
0
0
0
0
8
0
0
0
8
0
0
% Q
% Arg:
8
16
39
0
0
0
8
16
39
8
0
0
0
8
16
% R
% Ser:
0
0
8
0
16
8
16
47
0
0
8
8
0
0
8
% S
% Thr:
0
8
8
0
8
8
0
0
0
0
0
0
0
8
0
% T
% Val:
16
54
0
0
8
0
0
8
16
0
0
16
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
16
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _